中国临床药理学杂志Issue(9)：686-688,3.DOI:10.13699/j.cnki.1001-6821.2015.09.002
川芎嗪联合酚妥拉明治疗慢性肺源性心脏病心力衰竭的临床研究
Clinical effects of ligustrazine combined with phentolamine in the treatment of chronic pulmonary heart failure
摘要
Abstract
Objective To explore the clinical effects of ligustrazine combined with phentolamine in the treatment of chronic pulmonary heart failure.Methods A total of 78 cases with chronic pulmonary heart failure were randomly divided into control group ( n=38) and experiment group ( n =40 ).The include 78 cases were all treated with general treatment such as antibiotics, eliminating phlegm and so on.And patients in the experiment group were given phentolamine 10 mg with 5%glucose 250 mL through intravenous drop infusion bid for 10 days plus ligustrazine 240 mg with 5%glucose 250 mL by intravenous drop infusion qd for 10 days on the basic treatment of control group.The data of clini-cal symptom improvement, CI, PASP and blood gas index were compared between the two group before and after treatment.Results After treat-ment, the heart function in the experiment group was significantly improved than control group ( P<0.05 ).The pulmonary function such as PASP, PaCO2 , PaO2 and SaO2 in the two groups were significantly improved in both groups ( P <0.05 ).Conclusion Ligustrazine combined with phentolamine can significantly improve the clinical efficacy of patients with chronic pulmonary heart failure, with significantly improved heart function.关键词
慢性肺源性心脏病/心力衰竭/川芎嗪注射液/酚妥拉明Key words
chronic pulmonaly/heart failure/ligustrazine injection/phentolamine分类
医药卫生引用本文复制引用
蓝晓玲,马彩艳..川芎嗪联合酚妥拉明治疗慢性肺源性心脏病心力衰竭的临床研究[J].中国临床药理学杂志,2015,(9):686-688,3.基金项目
浙江省中医药科技计划基金资助项目 （）
