中国临床药理学杂志Issue(10)：893-896,4.DOI:10.13699/j.cnki.1001-6821.2015.10.038
肝X受体抗动脉粥样硬化作用机制研究进展
Research progress on antiatherosclerosis mechanism of liver X receptors
摘要
Abstract
Liver X receptor is a ligand -activated transcription factor of nuclear receptor super family .It played a key role in the regulation of lipid metabolism.In the past decade , numerous studies show that liver X receptor are involved in a series of physiological processes such as meta-bolism and inflammation by activating or inhibiting its target genes that are so closely linked with cardiovascular diseases .In recent years, a large number of studies have shown that liver X receptor are increasingly prominent in fighting against atherosclerosis . In this paper , we will review the targets of the LXR pathways on the pathogenesis of atherosclerosis.关键词
肝X受体/动脉粥样硬化/脂质代谢/炎症Key words
liver X receptor/atherosclerosis/lipid metabolism/inflammation分类
医药卫生引用本文复制引用
魏静,陈景瑞,苗琳,樊官伟..肝X受体抗动脉粥样硬化作用机制研究进展[J].中国临床药理学杂志,2015,(10):893-896,4.基金项目
国家自然科学基金资助项目（81273891）；教育部“创新团队发展计划”基金资助项目 （）
