中国临床药理学杂志Issue(11)：1038-1041,4.DOI:10.13699/j.cnki.1001-6821.2015.11.031
2012年全国三级医院胆汁培养病原菌的构成及耐药性分析
Bacterial distribution and resistance in biliary tract infections of the tertiary hospitals of China in 2012
摘要
Abstract
Objective To understand the bacteria distribution of biliary tract infections and drug resistance in China.Methods Antimicrobial susceptibility test for strains isolated from bile culture were performed in 557 hospitals in china.WHONET 5.6 software was used for statistical analysis.Results A total of 13596 bacterial strains were isolated, inclu-ding gram-positive cocci 3698 strains, accounting for 27.2%, gram-negative bacilli 9898 strains, accounting for 72.8%.The top two gram-positive cocci are Enterococcus faecalis 1237 strains (9.1%) and Entero-coccus faecium 1198 strains (8.8%).The top three gram-negative ba-cilli are Escherichia coli 4311 strains ( 31.7%) , Klebsiella pneumoniae 1518 strains ( 11.2%) and Pseudomonas aeruginosa 839 strains (6.2%) .The highest resistant rates of Escherichia coli and Klebsiella pneumoniae is ampicillin, amounting to 79.0% -87.1%; The resis-tance rates to cefotaxime of Escherichia coli and Klebsiella pneumoniae were 70.6% and 55.8 % respectively, and the resistance rates to cefepime were 28.7% and 18.4% respectively.The sensitive rates to imipenem and meropenem of Pseudomonas aeruginosa were 61.1% and 65.7%respectively.The resistance rates to vancomycin of Enterococcus faecalis and Enterococcus faecium were 2.5% and 1.3% respectively. Conclusion The most common pathogens of biliary infections are Escherichia coli, Klebsiella pneumonia, Pseudomonas aeruginosa and other Enterobacteriaceae.关键词
胆道感染/病原菌/抗菌药物/耐药Key words
biliary tract infection/pathogens/antibiotic/resistance分类
医药卫生引用本文复制引用
孙志,王鹏远,李威,鄢超,刘玉村,潘慧,徐雪松..2012年全国三级医院胆汁培养病原菌的构成及耐药性分析[J].中国临床药理学杂志,2015,(11):1038-1041,4.基金项目
国家科技支撑计划基金资助项目 （）
