中国临床药理学杂志Issue(11):1066-1068,3.DOI:10.13699/j.cnki.1001-6821.2015.11.039
Toll样受体4与糖尿病肾病的发病机制相关性的研究进展
Progress in search for relationship between Toll like receptor 4 with the pathogenesis of diabetic nephropathy
摘要
Abstract
So far, the etiology and pathogenesis of diabetic nephropathy have not been clear.Recent studies indicated that inflammatory factors play important roles in the pathogenesis and development of diabetic nephropathy.While Toll like receptor 4 can activate the downstream sig-nal molecules through the myeloid differentiation factor 88 ( MyD88 ) depen-dent and the MyD88 independent pathway, so as to induce immune responses.This article makes a new survey on the pathogene-sis of diabetic nephropathy inflammation and its relationship with Toll like receptor 4.关键词
糖尿病肾病/Toll样受体4/炎症Key words
diabetic nephropathy/Toll like receptor 4/inflammation分类
医药卫生引用本文复制引用
常微微,贺连平,姚应水..Toll样受体4与糖尿病肾病的发病机制相关性的研究进展[J].中国临床药理学杂志,2015,(11):1066-1068,3.基金项目
国家自然科学基金资助项目 ()