摘要
Abstract
Objective:To explore the analgesic efficacy of preoperative local injection of ropivacaine for patients receiving single port laparoscopic cholecystectomy .Methods:From December 2011 to August 2013 ,60 patients ,who received single port lapa‐roscopic cholecystectomy ,were randomly divided into experimental group and control group ,with 30 patients in each group . The difference in general information between the two groups was not statistically significant .Patients in two groups received education on visual analogue scale(VAS) one day before surgery .Patients in experimental group received preemptive analgesia with ropivacaine before the surgery and the detailed method was :2 mL 0 .375% ropivacaine was injected in the skin and subcu‐taneous tissue of umbilical incision;6 mL was injected to infiltrate fascia and muscle ,extraperitoneal space and parietal perito‐neum ;2 mL was locally injected in the tissue clamped by towel forceps on the both sides of the incision .Patients in the control group did not receive any treatment before surgery .Both two groups were identical in methods of the medication of anesthesia and the maintenance of anesthesia ,as well as the general anesthesia intubation .Patients’ vital signs and oxygen saturation was monitored with electrocardiogram monitor after surgery .VAS was evaluated at the moment when patients got fully awake after anesthesia ,and 2h ,4h ,8h ,12h ,24h after surgery .The postoperative application of analgesic and adverse events were recor‐ded .Results:The analgesic efficacy 0h ,2h ,4h ,8h after anesthesia recovery in experimental group was superior to that in con‐trol group(P<0 .05) ,and the times of application of analgesic in experimental group was less than that in control group(P<0 .05) .The difference in analgesic efficacy between the two groups was not statistically significant .The differences in surgery nausea ,vomiting and bronchospasm between the two groups were statistically significant (P<0 .05) .The differences in inci‐dence rates of dizziness ,drowsiness and respiratory depression between the two groups were not statistically significant(P>0 .05) .Conclusions:Preemptive analgesia with ropivacaine ,which is applied in local incision before surgery ,showed good anal‐gesic efficacy for patients who received single port laparoscopic cholecystectomy under general anesthesia .关键词
罗哌卡因/单孔腹腔镜胆囊切除术/超前镇痛Key words
Ropivacaine/Single port laparoscopic cholecystectomy/Preemptive analgesia分类
医药卫生
