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强直性脊柱炎遗传易感性基因的研究进展

张政 张毓洪 马玲玲 张玉荣 李星慧 杨泽

中国老年保健医学Issue(2):110-112,113,4.
中国老年保健医学Issue(2):110-112,113,4.DOI:10.3969/j.issn.1672-4860.2015.02.048

强直性脊柱炎遗传易感性基因的研究进展

Approach to ankylosing spondylitis genetic susceptibility genes

张政 1张毓洪 2马玲玲 1张玉荣 1李星慧 1杨泽2

作者信息

  • 1. 宁夏医科大学公卫学院 750004
  • 2. 卫生部北京医院,卫生部老年医学研究所 100730
  • 折叠

摘要

Abstract

Ankylosing spondylitis is a kind of autoimmune disease which have a genetic predisposition.In recent years, A num-ber of research found that AS incidence was rising in our country, and develops in adolescence, with 20 to 30 years old age group, has the highest incidence of AS disease, more men than women, the proportion is about 9:1, It has been a serious threat to the qual-ity of life of teenagers in our country.This review will be taken from the AS clinical symptoms, common complications and common methods for laboratory tests, etiology and mechanism, and AS infection related genetic factor is introduced.

关键词

强制性脊柱炎/基因/HLA-B27

Key words

Ankylosing spondylitis( AS)/genetic/HLA-B27

引用本文复制引用

张政,张毓洪,马玲玲,张玉荣,李星慧,杨泽..强直性脊柱炎遗传易感性基因的研究进展[J].中国老年保健医学,2015,(2):110-112,113,4.

基金项目

国家自然科学基金(81061120527,81370445,81472408),卫生部公益性研究基金(201302008)和国家科技部十二五支撑计划项目(2012BAI10B01)。 ()

中国老年保健医学

1672-2671

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