中国免疫学杂志Issue(5)：681-683,3.DOI:10.3969/j.issn.1000-484X.2014.05.025
Syk和VEGF-C在乳腺癌组织中的表达与淋巴结转移的关系
Syk and VEGF-C in breast cancer's expression with lymph node metastasis
张喜凤 1赵红兵2
作者信息
- 1. 商丘医学高等专科学校，商丘476100
- 2. 郑州大学第一临床医院，郑州 450052
- 折叠
摘要
Abstract
Objective:To explore the relationship of Syk and VEGF-C expression in breast cancer with lymph node metastasis . Methods:The expression of Syk and VEGF-C in 40 cases of breast cancer were determined using immunohistochemistry assay .Then, the positive rates of Syk and VEGF-C were compared with lymph node metastasis .Results:The expression rate of VEGF-C and Syk in breast cancer was respectively 77.5%(31/40), 37.5%(15/40).VEGF-C protein expression was not significant related with the tumor diameter (P>0.05) and histological grade (P>0.05), but was significantly associated with lymph node metastasis (P<0.05).Syk protein expression was not significant related with tumor diameter (P>0.05) and the histological grade(P>0.05), and was associated with lymph node metastasis (P<0.05).The difference of Syk and VEGF-C had statistics significance(P<0.05).Con-clusion:Syk and VEGF-C involved in the lymphatic invasion and metastasis , may be an important indicator of prognosis .关键词
乳腺癌/Syk/VEGF-CKey words
Breast cancer/Syk/VEGF-C分类
医药卫生引用本文复制引用
张喜凤,赵红兵..Syk和VEGF-C在乳腺癌组织中的表达与淋巴结转移的关系[J].中国免疫学杂志,2014,(5):681-683,3.
