中国免疫学杂志Issue(6)：827-830,4.DOI:10.3969/j.issn.1000-484X.2015.06.024
中性粒细胞CD64、CD32指数在肝硬化并自发性细菌性腹膜炎诊断中的价值
Evaluation of neutrophilic CD64 index and CD32 index as a diagnostic marker of liver cirrhosis with spontaneous bacterial peritonitis in early stage
邹金海 1孔祥军 1李春英 2孙鑫义 1刘晨第3
作者信息
- 1. 河北省沧州市中心医院核医学科，沧州 061001
- 2. 河北省沧州市中心医院中心实验室，沧州 061001
- 3. 河北省沧州市中心医院消化内科，沧州 061001
- 折叠
摘要
Abstract
Objective:To investigate the early diagnosis value of neutrophilic CD 64 index(nCD64 ID),neutrophilic CD32 index( nCD32 ID) in ascites and CRP in blood of liver cirrhosis patients combined with spontaneous bacterial peritonitis. Methods:The data of 156 cases with liver cirrhosis was analyzed retrospectively, which CD32 index, CD64 index and CRP were detected respectively and ROC curve analysis were performed. Results:The nCD64 ID,nCD32 ID and CRP in bacterial infection group were all significantly higher than that in no infection group(P<0. 001). The sensitivity and specificity of nCD32 ID,nCD64 ID and CRP were 82. 8%,96. 2%,72. 5% and 81. 0%, 95. 8%, 73. 1% respectively. Conclusion: The sensitivity and specificity of nCD64 ID were higher than nCD32 ID and CRP. The nCD64 ID can be used as an effective index for early diagnosis and differential diagnosis of liver cirrhosis combined with spontaneous bacterial peritonitis.关键词
肝硬化/自发性细菌性腹膜炎/中性粒细胞/CD32指数/CD64指数Key words
Liver cirrhosis/Bacterial infection/Neutrophile granulocyte/CD32 index/CD64 index分类
医药卫生引用本文复制引用
邹金海,孔祥军,李春英,孙鑫义,刘晨第..中性粒细胞CD64、CD32指数在肝硬化并自发性细菌性腹膜炎诊断中的价值[J].中国免疫学杂志,2015,(6):827-830,4.
