摘要
Abstract
Objective To investigate the application value of MR diffusion tensor imaging (DTI ) and simplified Fugl-Meyer (FM ) scale in old patients with acute cerebral infarction and hemiplegia. Methods Seventeen old patients with acute cerebral infarction and hemiplegia who met the inclusion criteria admitted to the Department of Neurology,the 305th Hospital of the People′s Liberation Army from November 2010 to April 2014 were enrolled prospectively. After admission,they were treated with rehabilitation therapy,including drugs in combination with practical training techniques for hemiplegia. After admission,the DTI examination and FM scale assessment were accomplished at the 1st,4th,and 12th weeks,respectively. Results There were significant differences in 3 times of DTI examinations between the contralateral/ipsilateral fractional anisotropy(FA)differences of the region of interest (ROI)and the differences of FM scale score (F=3. 437 and 3. 791 respectively;P<0. 01). In DTI of the acute cerebral infarction patients with hemiplegia,there was significant difference at the 1st week (0. 19 ± 0. 06)between the contralateral and ipsilateral FA difference of ROI compare with the 4th week (0. 13 ± 0. 04),(P>0. 05). There was no significant difference between the 4th and 12th week (0. 13 ± 0. 04)(P>0. 05). After drug and rehabilitation treatment,the FM scale scores showed that there was significant difference between the 1st week after admission (69 ±9)and the 4th week after admission (74 ±6),and between the 4thweek and 12week (82 ±10) (all P<0. 05). At the first time after admission,the corresponding contralateral/ipsilateral FA difference in ROI was negative correlated with that of the FM scale difference change at the first stage (4th week)before and after rehabilitation (rs = -0. 389,P<0.05). Conclusion Early application of DTI and FM in the prognostic evaluation of patients with cerebral infarction and hemiplegia has some predictive values.关键词
老年人/脑梗死/偏瘫/弥散张量成像/简化Fugl-Meyer运动功能量表Key words
Aged/Brain infarction/Hemiparalysis/Diffusion tensor imaging/Fugl-Meyer scale,simplified
