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微透析技术应用于胰腺研究的现状与展望

王丹 刘春生 周丁华 常子倩(综述) 李爱民(审校)

中国普通外科杂志Issue(3):413-417,5.
中国普通外科杂志Issue(3):413-417,5.DOI:10.3978/j.issn.1005-6947.2015.03.021

微透析技术应用于胰腺研究的现状与展望

Microdialysis applied in pancreas research:current status and future prospects

王丹 1刘春生 2周丁华 3常子倩(综述) 1李爱民(审校)3

作者信息

  • 1. 中国人民解放军第二炮兵总医院 药剂科,北京 100088
  • 2. 中国人民解放军第二炮兵总医院 骨科,北京 100088
  • 3. 中国人民解放军第二炮兵总医院 肝胆外科,北京 100088
  • 折叠

摘要

Abstract

Microdialysis (MD) is a biochemical micro-detection technique that can continuously sample and analyze the endogenous or exogenous substances in the intercellular lfuid, with no impact on the internal environment of the organism. MD can be used to determine not only the local drug pharmacokinetics in internal organs or tumors but also the pathophysiological processes that have metabolic products or organ specificity, and even may be used as an approach for direct delivery and assessment of the local drug in organs and tumors. In this paper, the authors address the application of MD in dealing with pancreas-related research, and discuss its advantages and limitations, as well as the future prospects.

关键词

胰腺/微透析技术/综述文献

Key words

Pancreas/Microdialysis/Review

分类

医药卫生

引用本文复制引用

王丹,刘春生,周丁华,常子倩(综述),李爱民(审校)..微透析技术应用于胰腺研究的现状与展望[J].中国普通外科杂志,2015,(3):413-417,5.

中国普通外科杂志

OA北大核心CSCDCSTPCD

1005-6947

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