中国全科医学Issue(13)：1524-1528,1537,6.DOI:10.3969/j.issn.1007-9572.2014.13.020
有氧运动对乳腺癌患者癌因性疲乏疗效的 Meta 分析
Effects of Aerobic Exercise on Cancer-related Fatigue in Breast Cancer Patients Receiving Chemotherapy:A Meta-analysis
摘要
Abstract
Objective Studies show that aerobic exercise may receive cancer - related fatigue of breast cancer patients undergoing chemotherapy,but some with controversial results. This meta - analysis is aimed to explore the intervention effects of aerobic exercise on CRF in breast cancer patients receiving chemotherapy. Methods A literature search of PubMed,Embase, CISCOM,CINAHL,Google Scholar,CNKI and CBM databases was conducted on articles published before September 1st, 2013. STATA 12. 0 software was used for the meta - analysis. Crude standardized mean difference(SMD)and its 95% confidence interval(CI)were calculated,and according to the results the association of the two was assessed. Results Twelve cases were brought into the comparative studies with a total of 1 014 breast cancer patients receiving chemotherapy,including 522 patients in the aerobic exercise group(the intervention group)and 492 patients in the usual care group(the control group). The meta - a-nalysis results revealed that the RPFS scores of breast cancer patients in the intervention group were significantly lower than those in the control group〔SMD = - 0. 82,95% CI( - 1. 04, - 0. 60),P ﹤ 0. 001〕. However,there was no significant difference in FACIT - F scores between the intervention and control groups〔SMD = 0. 09,95% CI( - 0. 07,0. 25),P = 0. 224〕. Sub-group analysis by ethnicity indicated that there were significant differences in RPFS and FACIT - F scores between the intervention and control groups among Asian populations〔RPFS:SMD = - 1. 08,95% CI( - 1. 35, - 0. 82),P ﹤ 0. 001;FACIT - F:SMD = 1. 20,95% CI(0. 70,1. 71),P ﹤ 0. 001〕,but no significance among Caucasian populations(P ﹥ 0. 05). Conclu-sion The current meta - analysis indicates that aerobic exercise may improve cancer - related fatigue in breast cancer patients re-ceiving chemotherapy,especially among Asian populations.关键词
有氧运动/癌因性疲乏/乳腺肿瘤/化疗/Meta 分析Key words
Aerobic exercise/Cancer - related fatigue/Breast neoplasms/Chemotherapy/Meta - analysis分类
医药卫生引用本文复制引用
邹凌云,杨柳,何晓玲,宋祎,徐锦江..有氧运动对乳腺癌患者癌因性疲乏疗效的 Meta 分析[J].中国全科医学,2014,(13):1524-1528,1537,6.基金项目
辽宁省科技厅课题 （）
