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首页|期刊导航|中国全科医学|蛋白质组学在肥胖和胰岛素抵抗及2型糖尿病中的应用研究进展

蛋白质组学在肥胖和胰岛素抵抗及2型糖尿病中的应用研究进展

王铭婕 闫朝丽

中国全科医学Issue(21):2524-2527,4.
中国全科医学Issue(21):2524-2527,4.DOI:10.3969/j.issn.1007-9572.2014.21.027

蛋白质组学在肥胖和胰岛素抵抗及2型糖尿病中的应用研究进展

Research Progress on the Application of Proteomics in Obesity, Insulin Resistance and Type 2 Diabetes

王铭婕 1闫朝丽2

作者信息

  • 1. 010059内蒙古呼和浩特市,内蒙古医科大学
  • 2. 内蒙古医科大学附属医院内分泌科
  • 折叠

摘要

Abstract

Withtheimprovementofpeople′slivingstandards,obesityhasbecominganimportantfactoraffecting health.The relationship between obesity , insulin resistance and type 2 diabetes is close , which is often considered as a continu-ous phase of disease development .On the base of the whole protein , proteomics can discover more deeper and more close life es-sence, and can explore the basic laws of life activities and mechanisms of disease , the major proteomic techniques consist of di-mensional electrophoresis and mass -spectrography.This article focuses on the progress of the current proteomic techniques , em-phatically introduces research progress on the application of proteomics in obesity , insulin resistance and type 2 diabetes, by de-tecting some relevant markers , providing a new insights into the study of type 2 diabetes.

关键词

蛋白质组学/肥胖/胰岛素抵抗/糖尿病,2型

Key words

Proteomics/Obesity/Insulinresistance/Diabetesmellitus,type2

分类

医药卫生

引用本文复制引用

王铭婕,闫朝丽..蛋白质组学在肥胖和胰岛素抵抗及2型糖尿病中的应用研究进展[J].中国全科医学,2014,(21):2524-2527,4.

基金项目

中华医学会临床医学科研专项基金资助 ()

中国全科医学

OA北大核心CSCDCSTPCD

1007-9572

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