中国全科医学Issue(24)：2851-2854,4.DOI:10.3969/j.issn.1007-9572.2014.24.017
北京地区育龄期妇女TORCH筛查结果调查分析
Analysis on TORCH Screening Results among Women at Childbearing Age in Beijing
龙彦 1赵晓涛 1孙媛媛 1刘畅 1王辉1
作者信息
- 1. 100044北京市，北京大学人民医院检验科
- 折叠
摘要
Abstract
Objective To analyze anti-TORCH antibodies among women at childbearing age in Beijing in order to provide reference for the healthcare of women at childbearing age. Methods 6 978 women received preconception screening and pregnancy screening in Peking University Peopleˊs Hospital from November 2012 to November 2013 were given anti-TORCH test with CLIA. Results The highest seropositive rate was anti-HSVⅠ/ⅡIgM〔11. 19%(779/6 962)〕,which was significantly higher than the other three pathogens,and the difference was statistically significant(P all<0. 007). It was followed by anti-RV IgM and anti-CMV IgM,whose seropositive rate was 2. 63%(176/6 691)and 2. 54%(167/6 564)respectively,showing no statistically significant difference(P=0. 755). Anti-TOX IgM had the lowest seropositive rate〔0. 62%(41/6 601)〕, showing statistically significant difference( P <0. 007 ) . The results showed a higher prevalence of anti -HSVⅠ/Ⅱ IgM in spring and autumn〔12. 48%(280/2 244)and 12. 41%(195/1 571),respectively〕,while the seropositive rate of anti-CMV IgM was significantly higher in autumn〔3. 66%(541/1 475)〕than other seasons(P<0. 007). The seropositive rate of anti-TOX IgM and anti-RV IgM in different seasons showed no statistically significant difference( P . 0. 05 ) . All the cases were divided into young group( <35 years)and old group(≥35 years). The seropositive rate of anti-HSVⅠ/ⅡIgM in the young group was higher than in the old group(χ2 =31. 934,P=0. 000),while the seropositive rate of anti-CMV IgM in the old group was higher than in the young group(χ2 =7. 888,P=0. 005),and the seropositive rate of anti-TOX IgM in the old group was higher than in the young group(χ2 =8. 929,P=0. 003). The seropositive rate of anti-RV IgM showed no statistically sig-nificant difference between the two groups(χ2 =3. 012,P=0. 083). Among the women surveyed,the anti-CMV IgG had the highest seropositive rate at 84. 36%(2 455/2 910)(P<0. 05),and the anti-TOX IgG had lowest seropositive rate at 1. 22%(27/2 216)(P<0. 05). Conclusion The seropositive rate of TORCH is fairly high among women at childbearing age in Bei-jing. It is necessary to adopt new approaches conduct preconception and pregnancy test to prevent congenital TORCH infection.关键词
单纯疱疹病毒/风疹病毒/巨细胞病毒/弓形虫属/免疫球蛋白M/免疫球蛋白G/抗体Key words
Simplexvirus/Rubella virus/Cytomegalovirus/Toxoplasma/Immunoglobulin M/Immunoglobulin G/Antibodies分类
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龙彦,赵晓涛,孙媛媛,刘畅,王辉..北京地区育龄期妇女TORCH筛查结果调查分析[J].中国全科医学,2014,(24):2851-2854,4.
