中国全科医学Issue(24)：2895-2896,2900,3.DOI:10.3969/j.issn.1007-9572.2014.24.030
颅盖骨孤立性浆细胞瘤一例并文献复习
Solitary Plasmacytoma of the Calvarium:A Case Report and Literature Review
焦风 1刘波 1梁冶矢1
作者信息
- 1. 100044北京市，北京大学人民医院神经外科
- 折叠
摘要
Abstract
Solitary craniocerebral location is the least frequent of all extramedullary solitary plasmacytomas. Solitary plasmacytoma of the calvarium is even more rare. We retrospectively analyzed the clinical manifestation and prognosis of a male pa-tient presented with solitary plasmacytoma of the calvarium and reviewed the current related literatures. This is a middle-aged male patient whose history was painless tumor of occipital location for 6 months. Computed tomography ( CT)and magnetic reso-nance image( MRI)showed occipital mass with bony destruction,but the dura and brain were not involved. The patient accepted spread surgical resection and cranioplasty. Histological examination confirmed plasmacytoma. Postoperative myeloma work-up was done,the results were normal. Bone marrow aspiration showed no evidence of systemic myeloma. The patient did not receive the radiotherapy or chemotherapy. After 24 months followed-up,the tumor showed no local recurrence but unfortunately progressed to multiple myeloma. Totally 54 cases were reviewed of solitary plasmacytoma of the calvarium. 52 patients(96. 3%)were treated with surgery or together with radiotherapy,but only 10 patients(18. 5%)transformed to multiple myeloma. Our study showed that solitary calvarial plasmacytomas have generally good prognosis,whereas several patients invariably progress to multiple mye-loma at some stage. Radical surgery followed by radiation is the best treatment option available at present.关键词
颅骨/浆细胞瘤/颅骨肿瘤/多发性骨髓瘤Key words
Skull/Plasmacytoma/Skull neoplasms/Multiple myeloma分类
医药卫生引用本文复制引用
焦风,刘波,梁冶矢..颅盖骨孤立性浆细胞瘤一例并文献复习[J].中国全科医学,2014,(24):2895-2896,2900,3.
