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铁调素与慢性肾脏病关系的研究进展

刘旭 丁嘉祥 刘文虎

中国全科医学Issue(25):3025-3027,3.
中国全科医学Issue(25):3025-3027,3.DOI:10.3969/j.issn.1007-9572.2014.25.030

铁调素与慢性肾脏病关系的研究进展

Research Advances in Relationship between Hepcidin and Chronic Kidney Disease

刘旭 1丁嘉祥 1刘文虎1

作者信息

  • 1. 100050北京市,首都医科大学附属北京友谊医院肾内科,首都医科大学肾病学系
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摘要

Abstract

Hepcidinisanimportantregulatorforironhomeostasis,whichcandecreasetheserumironlevel.Serum hepcidin levels will increase in patients with chronic kidney diseases,which may contribute to the development and severity of a-nemia,and resistance to erythropoietin. Anemia may be corrected by releasing the iron reserve through reducing hepcidin levels or suppressing hepcidin signaling pathway in patients with chronic kidney diseases. However,clinical safety of anti-hepcidin thera-py still requires further investigation.

关键词

铁调素/慢性肾脏病/贫血

Key words

Hepcidin/Chronickidneydisease/Anemia

分类

医药卫生

引用本文复制引用

刘旭,丁嘉祥,刘文虎..铁调素与慢性肾脏病关系的研究进展[J].中国全科医学,2014,(25):3025-3027,3.

基金项目

国家科技支撑计划课题项目(2O11BAI1OBO2);北京市科技计划课题项目 ()

中国全科医学

OA北大核心CSCDCSTPCD

1007-9572

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