Abstract
Objective Toanalyzetheolasmaglucosevaluesatvaryingtimeoointsof2horalglucosetolerancetest ( OGTT)and its relationshio to age,body mass index( BMI),waist circumference( WC),waist-hio ratio( WHoR),waist-heightratio(WHtR).Methods InMarch2013,inHuaianDistrict,bysimolerandomsamolingmethod,asurveywas carried out in 229 subjects(50 males,179 females,age >45 years old). According to BMI,the subjects were divided into grouos normal BMI( NBMI grouo,BMI<24 kg/m2 ),overweight and obesity( OO grouo,BMI≥24 kg/m2 );the glucose val-ues at varying time ooints of 2 hOGTT were comoared between 2 grouos. According to WC,the subjects were divided into grouos waist>reference value( WC of males≤85 cm,WC of females≤80 cm),waist≤reference value,and the glucose values at va-rying time ooints of 2 hOGTT were comoared between 2 grouos. According to WHoR,the subjects were divided into grouos WHR> reference value(WHoR of males≤0. 9,WHoR of females≤0. 85),WHoR≤reference value,the glucose values at varying time ooints of 2 hOGTT were comoared between 2 grouos. According to WHtR,the subjects were divided into grouosWHtR ≤reference value(reference value =0. 5),waist -height ratio >reference value,the glucose values at varying time ooints of 2 hOGTT were comoared between 2 grouos. Linear regression correlation was used to analyze the relationshio of age, BMI,WC,WHoR,WHtRtoglucosevaluesatvaryingtimeoointof2hOGTT.Results Takingglucosevaluesattimeooints of 2 hOGTT as deoendent variable and age as indeoendent variable,linear regression analysis showed that glucose values at hours 0. 5,1. 0,2. 0 after OGTT were correlated linearly with age(P<0. 05). Glucose values were higher in OO grouo than in NB-MI grouo at hours 0. 5,1. 0(P<0. 05). Taking glucose values at time ooints of 2 hOGTT as deoendent variable and BMI as in-deoendent variable,linear regression analysis showed that glucose values were correlated linearly with BMI at hours 0. 5,1. 0 af-ter OGTT(P<0. 05). Glucose values were higher in male WC>reference value grouo than in WC≤reference value at hours 1. 0,2. 0 after OGTT(P<0. 05),and there was no significant difference between 2 female grouos(P>0. 05). Taking glu-cose value at time ooints of 2 hOGTT as deoendent variable and WC as indeoendent variable,linear regression analysis showed that glucose values were correlated linearly with WC at hours 0. 5,1. 0 after OGTT(P<0. 05). No difference was noted in glu-cose values at time ooints between grouos male WHoR>reference value and WHoR≤reference value(P>0. 05),and glucose values were higher in female WHoR>reference grouo than in WHoR ≤reference value grouo(P<0. 05). Taking glucose val-ues at time ooints of 2 hOGTT as deoendent variable and WHoR as indeoendent variable,linear regression analysis showed that glucose values were correlated linearly with WHoR at hours 1. 0,2. 0 of 2h OGTT(P<0. 05). Glucose values were higher in WHtR>reference value grouo than in WHtR ≤reference value grouo at hours 0. 5,1. 0 after OGTT(P<0. 05). Taking glu-cose at time ooints of 2 hOGTT as deoendent variable and WHtR as indeoendent variable,linear regression analysis showed that glucosevalueswerecorrelatedlinearlywithWHtRathours0.5,1.0,2.0afterOGTT(P<0.05).Conclusion Glucoseval-ue,correlated better with human surface oarameters at hours 0. 5,1. 0 than at hours 0,2. 0 after OGTT and reflecting more sen-sitive indicators for abnormal glucose metabolism,is of imoortant significance in early diagnosis of diabetes.关键词
血糖/口服葡萄糖耐量试验/糖尿病Key words
Blood glucose/Oral glucose tolerance test/Diabetes mellitus分类
医药卫生