摘要
Abstract
Objective To explore the clinical application value of two-dimensional ultrasound and acoustic radiation force impulse( ARFI)imaging technology in the differential diagnosis of benign and malignant breast masses. Methods From October 2012 to October 2013,eighty-one patients received breast surgical operation in the First Affiliated Hospital of Shihezi University Medical College and postoperative pathological examinations( gold standard)showed the masses of 42 cases were be-nign(47 lesions,benign group),39 cases were malignant(39 lesions,malignant group). The features of two-dimensional Ultrasound and ARFI impulse image photos of the lesions were analyzed. Ultrasound features including shape,speculated mar-gin,internal echo,micro-calcification,aspect ration,grade of blood flow,resistance index( RI),virtual touch tissue ima-ging( VTI)and virtual touch tissue quantification( VTQ)were selected to be compared with pathological results by Kappa. Re-sults There were statistical significances of shape,speculated margin,aspect ratio、grade of blood flow,resistance index dis-tribution between the two groups(P<0. 05). The aspect ratio of malignant group was(0. 71 ± 0. 23),which was higher than that of benign group(0. 56 ± 0. 17),and the difference was significant(t =5. 134,P <0. 05). RI of malignant group was (0. 78 ±0. 13),which was higher than that of benign group(0. 64 ±0. 12),and the difference was significant(t=6. 348,P<0. 05). The differences of VTI evaluation score and VTQ distribution of the masses were statistically different between the two groups(Z= -6. 490,t=8. 178;P<0. 05). When VTQ=4 m/s was used as the cut point for separating benign from malig-nant,sensitivity was 76. 9%(30/39)and specificity was 93. 6%(44/47). When VTI=4 was used as the cut point for the separation,sensitivity was 89. 7%( 35/39 ) and specificity was 68. 1%( 32/47 ). Comprehensive analysis showed that the sensitivity of two-dimensional ultrasound and ARFI technology was 89. 7%(35/39),specificity was 93. 6%(44/47) and accuracy was 91. 8%. The comparison of combined ultrasound results and pathological examination showed that Kappa=0. 835. Conclusion Combination of two-dimensional ultrasound,color doppler flow imaging and acoustic radiation force impulse has better significant clinical value than single use of anyone aboveultrasonic sign in the differential diagnosis of breast mass.关键词
乳腺肿块/二维超声/超声检查,多普勒,彩色/声脉冲辐射力成像技术/诊断,鉴别Key words
Breast mass/Two - dimensional ultrasound/Ultrasonography, doppler, color/Acoustic radiation force impulse imaging technology/Diagnois,differential分类
医药卫生
