中国全科医学Issue(33)：3974-3978,5.DOI:10.3969/j.issn.1007-9572.2014.33.018
经皮穿刺椎体成形术治疗脊柱肿瘤疗效及安全性的 Meta 分析
Efficacy and Safety of Percutaneous Vertebroplasty Treatment of Spinal Tumors:A Meta -analysis
钟远鸣 1程俊 2张家立 1李智斐 1仇振茂 2付拴虎 2卢大汉 2杨高杰2
作者信息
- 1. 530023 广西南宁市，广西中医药大学第一附属医院脊柱外科
- 2. 广西中医药大学
- 折叠
摘要
Abstract
Objective To evaluate the efficacy and safety of Percutaneous vertebroplasty for spinal tumors. Methods We searched for articles about the researches on the treatment of spinal tumors by PVP in PubMed,CBM,CNKI,Wanfang full- text database and VIP. RevMan 5. 2 was used to analyze pain intensity visual analogue scale(VAS),pain relief,function re-covery,survival rate,economic benefits(hospital cost and length of stay)within each research. Results 9 randomized control trials were included in the study with a total of 1 022 cases of patients. The literature quality was low. Meta - analysis showed that:after treatment of spinal tumors by PVP(in the experimental group)and other treatments including open surgery,chemotherapy, kyphoplasty( in the control group),VAS all had obvious improvement but no statistic significance in effectiveness was found be-tween the two groups(P = 0. 33);no significant differences in function recovery and complication rates were found between the experimental group and the control group(P = 0. 38;P = 0. 85). But in terms of pain relief,survival and economic benefits(in-cluding hospital costs,length of stay),PVP group was better than the control group,with significant difference(P < 0. 05). Conclusion PVP treatment of spinal tumors has a good analgesic effect with better pain relief,satisfying economical results, and higher survival rate. However,clinical reports about the observed indexes are not enough,so meta - analysis is still lack of convincingness and more strict studies are needed to prove the results.关键词
脊柱/骨肿瘤/肿瘤转移/椎体成形术/随机对照试验/Meta 分析Key words
Spine/Bone neoplasms/Neoplasms metastasis/Vertebroplasty/Randomized controlled trial/Meta -analysis分类
医药卫生引用本文复制引用
钟远鸣,程俊,张家立,李智斐,仇振茂,付拴虎,卢大汉,杨高杰..经皮穿刺椎体成形术治疗脊柱肿瘤疗效及安全性的 Meta 分析[J].中国全科医学,2014,(33):3974-3978,5.
