摘要
Abstract
Objective To explore the clinical effects and application values of fractional flow reserve( FFR) in guid-ing coronary intervention for critical lesions. Methods 43 patients with coronary critical lesions received CAG evaluation and FFR in Xinjiang TCM Hospital from January to June 2013 were divided into groups according to FFR values( taking 0. 75 as di-viding value). The patients with FFR≥0. 75 were divided into defer PCI group( given drug treatment),the patients with FFR<0. 75 were divided randomly into groups drug treatment( DT group;given aspirin,clopidogrel,statins),PCI +DT group (PCI group). The patients were followed up in months 6 after treatment to observe the major adverse cardiac events(MACE) and recurrence of angina pectoris( AP). Results According to FFR values,there were 12 cases in PCI+DT group,11 in DT group,20 in defer PCI group. There was no significant difference in gender,age,smoking rate,hypertension,diabetes,hy-perlipidemia,the proportion of family history,ejection fraction,drug use during hospitalization or in months 6 after treatment a-mong 3 groups(P>0. 05);there was no difference in diseased region,reference diameter,angiostegnosis percentage,mini-mum lumen diameter(P>0. 05). In the follow-up in months 6 after treatment,no cardiac sudden death,myocardial infarc-tion occurred in 3 groups,there was no patient having revascularization in groups PCI+DT,defer PCI,but there were 2 cases (18. 0%)in DT group. There was no difference in rate of AP recurrence(P=0. 832). Conclusion In dealing critical le-sions in coronary intervention,FFR values do not increase MACE but can guide PCI treatment better.关键词
冠状动脉介入治疗/临界病变/血流储备分数Key words
Coronary intervention/Critical lesions/Fractional flow reserve分类
医药卫生
