摘要
Abstract
Objective To assess the effects of seasonal factors on serum 25 -hydroxyvitamin D〔25(OH)VitD〕levels in people living in Guangzhou. Methods Between January 2013 and December 2013,the 25(OH)VitD serum level was assessed in 2 205 people living in Guangzhou. The subjects according to examination month,calculated 25(OH)VitD lev-el every month,adjusted with gender,age,BMI,and analyzed combined with solar radiation,sunshine hours,rainfall amount in January to December 2013. Additionally,the proportion of VitD sufficiency(75 nmol/L or higher),insufficiency(50- <75 nmol/L)and deficiency( <50 nmol/L)monthly were estunated. Results Taking serum 25(OH)VitD as dependent variable and gender,age,BMI as independent variables,multiple linear regression analysis showed that age,gender and BMI did not effect serum 25(OH)VitD(P>0. 05). There was no significant difference in gender,age,BMI,SBP,DBP in va-rying months(P>0. 05). The average level of 25(OH)VitD was(53. 7 ±19. 0)nmol/L. The minimum value of 25(OH) VitD was(47.5 ±17.4)nmol/L,appearing in April;the maximum value was(59.8 ±20.2)nmol/L,appearing in Octo-ber. The minimum value of solar radiation was(202. 0 ± 105. 0)Wh/m2,appearing in April;the maximum was(507. 0 ±108. 1)Wh/m2,appearing in September. The minimum value was(41. 0 ± 31. 4)h,appearing in April,the maximum was(203. 7 ± 58. 9) h,appearing in September. The constituent ratio of yearly VitD deficiency was 49. 16%(1 084/2 205), there was difference in months(χ2 =65. 342,P<0. 010),higher in April than in the other months,lower in October than in the other months(P<0. 05). The constituent ratio of yearly VitD sufficiency was 16. 92%(373/2 205),there was difference in each month(χ2 =7. 491,P=0. 021). Thereinto higher in October than in the other months(P<0. 05). Conclusion VitD defficiency is very common in people living in Guangzhou and seasonal changes influence 25(OH)VitD level.关键词
25-羟基维生素D/季节/辐射/广州Key words
25(OH)VitD/Seasons/Radiation/Guangzhou分类
医药卫生
