中国全科医学Issue(2)：184-190,7.DOI:10.3969/j.issn.1007-9572.2015.02.015
腹腔镜和开腹在早期卵巢癌全面分期手术中疗效的Meta 分析
Laparoscopic and Laparotomy in Staging Operation of Early-stage Ovarian Cancer:A Meta-analysis
摘要
Abstract
Objective To compare the effects of laparoscopic(LPS)and laparotomy(LPT)on early ovarian cancer in staging operation. Methods PubMed,EMBase,Cochrane Library,Wan - fang database,Chinese Biomedical Abstracts database,China National Knowledge Infrastructure were retrieved for literatures on the effects of LPS,LPT on early ovarian cancer in staging operation from 1990 - 01 - 01 to 2014 - 02 - 12. RevMan 5. 2. 9 software was used to analyze the operative time,intraoperative blood loss,number of lymph node dissection,incidence of intraoperative tumor rupture,postoperative anal exhaust time,incidence of surgical complications,postoperative pain scores(VAS),hospital stay,recurrence rate,mortality. Results A total of 18 controlled clinical studies were enrolled including 434 LPS patients and 788 LPT patients. The blood loss was less in LPS group than in LPT group〔MD = - 207. 86,95% CI( - 285. 87, - 129. 86),P < 0. 05〕,anal exhaust time earlier〔MD = - 25. 26,95% CI( - 31. 07, - 19. 45),P < 0. 05〕,surgical complication incidence lower〔 OR = 0. 30, 95% CI(0. 20,0. 45),P < 0. 05〕,pains fewer〔 MD = - 2. 84,95% CI( - 4. 39, - 1. 29),P < 0. 05〕,hospital stay shorter〔MD = - 4. 14,95% CI( - 4. 63, - 3. 66),P < 0. 05〕,but there were no significant difference in surgical time, number of lymph node dissection,intraoperative tumor rupture,postoperative recurrence rate,mortality between two groups(P> 0. 05). Conclusion Laparoscopic staging operation of early ovarian cancer with small surgical traumas and quick recovery is not remarkably different from LPT.关键词
卵巢肿瘤/腹腔镜外科手术/剖腹术/治疗结果/Meta 分析Key words
Ovarian neoplasms/Laparoscopy surgical procedures/Laparotomy/Treatment outcome/Meta - analysis分类
医药卫生引用本文复制引用
赵鲁文,宋晓莉,于爱军,毛淑芳,张玉娟..腹腔镜和开腹在早期卵巢癌全面分期手术中疗效的Meta 分析[J].中国全科医学,2015,(2):184-190,7.基金项目
河北省承德市科学技术研究与发展计划 （）
