摘要
Abstract
Objective To determine the effect of early enteral nutrition with probiotic on blood lipid and high -sensitivity C - reactive protein( hs - CRP) in critically ill patients in intensive care unit. Methods From August 2012 to October 2013,in the First Affiliated Hospital of Xinjiang Medical University,45 critically ill patients were divided randomly into groups study(n = 23;3 patients were excluded due to leaving hospital without cure or surviving < 7 d),control( n = 22). The 2 groups were given nutrition support of enteral nutrient solution by nasogastric feeding tubes,the study group given probiotics based on it at hours 24 - 48 h after ICU treatment. The levels of triglyceride( TG),total cholesterol( TC),high density lipoprotein cholesterol( HDL - C),low density lipoprotein cholesterol( LDL - C) and hs - CRP were determined before treatment and on days 7 of treatment. Results There was no significant difference in gender,age,BMI,APACHE Ⅱ, disease constitution between 2 groups(P > 0. 05),no in levels of TG,TC,LDL - C,HDL - C,hs - CRP before treatment (P > 0. 05),and no in TC,LDL - C after treatment(P > 0. 05),the levels of TG,hs - CRP were lower,HDL - C higher in study group than in control group(P < 0. 05). Conclusion Enteral nutrition with probiotics is conducive to improving blood lipid level in critically ill patients and can reduce inflammation,thereby to decrease the risks of cardiovascular diseases.关键词
肠道营养/益生菌/危重病人医疗/血脂/超敏 C 反应蛋白Key words
Enteral nutrition/Probiotic/Critical care/Lipid/High - sensitivity creactive protein分类
医药卫生
