中国全科医学Issue(3)：300-303,4.DOI:10.3969/j.issn.1007-9572.2015.03.014
肝癌患者肝动脉化疗栓塞术后恶心呕吐的非化疗影响因素分析
Non - chemotherapy Intluence Factors tor Nausea and Vomiting among Hepatocellular Carcinoma Patients atter Transarterial Chemoembolization
摘要
Abstract
Objective To analyse non - chemotherapy influence factors for nausea and vomiting among hepatic carcinoma patients after transarterial chemoembolization( TACE). Methods According to Inclusion and exclusion criteria, 272 hepatic carcinoma patients who were admitted to Intervention Ward of First Hospital Affiliated to China Medical University from October 2012 to October 2013,were selected as study subjects. Age,gender,neoplasm metastasis,tumor size,dose of iodinated oil injection,pain degree,duration of pain,the number of interventional operation,fever degree,duration of fever, and abdominal distension of patients were recorded,the relationship between the above indicators and nausea and vomiting after TACE was analysed. Results 272 cases were graded using NVSD classification system,169 cases(62. 1% )were grade 0,59 (21. 7% )were grade 1,44(16. 2% )were grade 2. Age was negatively correlated with nausea and vomiting(r = - 0. 217,P﹤ 0. 05 ); pain degree, duration of pain, abdominal distension were negatively correlated with nausea and vomiting, respectively(r = 0. 333,0. 538,0. 188,P ﹤ 0. 05). According to multivariate Logistic regression analysis results,advanced age was protective factors for nausea and vomiting after TACE〔 OR = 0. 916,95% CI(0. 841,0. 998),P = 0. 044〕;both long duration of pain and abdominal distension were independent protective factors for nausea and vomiting after TACE〔OR =373. 019,95% CI(8. 197,16 974. 798),P = 0. 002;OR = 3. 677,95% CI(1. 064,12. 702),P = 0. 040〕. Factors about pain had positive direct influence on nausea and vomiting(β = 0. 42,P ﹤ 0. 01),nausea and vomiting had direct positive direct influence on abdominal distension(β = 0. 77,P ﹤ 0. 01);age had negative influence on pain(β = - 0. 01,P = 0. 072), while age had positive influence on abdominal distension(β = 0. 01,P = 0. 069);the effects of age and abdominal distension on nausea and vomiting were not significant( P ﹥ 0. 05). Conclusion Age,duration of pain and abdominal distension have influence on occurence of nausea and vomiting among hepatic carcinoma patients,the occurrence of nausea and vomiting among hepatic carcinoma patients after TACE is the result of multiple factors.关键词
肝肿瘤/肝动脉化疗栓塞术/手术后恶心呕吐/影响因素Key words
Liver neoplasms/Transarterial chemoembolization/Postoperative nausea and vomiting/Influence factors分类
医药卫生引用本文复制引用
臧爽,徐阳..肝癌患者肝动脉化疗栓塞术后恶心呕吐的非化疗影响因素分析[J].中国全科医学,2015,(3):300-303,4.基金项目
辽宁省科学技术计划项目 （）
