中国全科医学Issue(12)：1366-1370,5.DOI:10.3969/j.issn.1007-9572.2015.12.004
灯盏生脉胶囊改善缺血性脑卒中患者预后的前瞻性非随机同期病例对照研究
Impact of Dengzhanshengmai Capsule on Prognosis of Ischemic Stroke Patients:A Prospective,Non - randomized, Homeochronous,Case-control Study
摘要
Abstract
were compared between two groups of patients. Results There was no significant difference in mortality and the incidence of vascular events between two groups 1,3,and 6 months after treatment,respectively(P > 0. 05). After 12 - months follow -up,there was no significant difference in mortality between control group〔5. 09% (11 / 216)〕and treatment group〔3. 24%(7 / 216)〕(P > 0. 05). After 12 - months follow - up,incidence of vascular events in control group〔10. 19% (22 / 216)〕was significantly higher than that〔4. 63% (10 / 216)〕in treatment group(P < 0. 05). After 12 - months follow - up,there was significant difference in mRS score between two groups(u = 2. 119,P = 0. 034). Before treatment,there was no significant difference in NIHSS score,blood pressure,levels of blood glucose,total cholesterol(TC),triglycerides(TG),LDL - C and HDL - C between two groups( P > 0. 05) . After 12 - months follow - up,levels of TC and TG in treatment group was significantly lower than those in control group(P < 0. 05). For treatment group,NIHSS score,levels of TC,TG and LDL - C after 12 - months follow - up was significantly lower than those before treatment( P < 0. 05). Conclusion Compared with routine western medicine treatment,Dengzhanshengmai capsule combined with secondary prevention therapy of ischemic stroke can substantially reduce the incidence of vascular events in ischemic stroke,reduce the mRS score,modulate the cholesterol level and improve the prognosis of patients.关键词
卒中/灯盏生脉胶囊/预后/血脂异常/病例对照研究Key words
Stroke/Dengzhanshengmai capsules/Prognosis/Dyslipidemias/Case - control studies分类
医药卫生引用本文复制引用
蔡业峰,乔寒子,卢鸿基,叶日春,陈燕华,周子懿..灯盏生脉胶囊改善缺血性脑卒中患者预后的前瞻性非随机同期病例对照研究[J].中国全科医学,2015,(12):1366-1370,5.基金项目
广东省科学技术厅-广东省中医药科学院联合科研专项（20120332）；广东省医学科学技术研究基金（ B2012158）；广东省中医院院内专项课题［中医二院（2011）268号，中医二院（2013）83号］ （）
