摘要
Abstract
Objective To investigate the application status and development trend of antiepileptic drugs( AEDs)in a hospital in Hubei. Methods Statistical analyses were conducted on the 2010—2013 data of AEDs in Taihe Hospital in Shiyan. The data included drug varieties,sales amount,defined daily doses( DDDs),defined daily cost( DDC),annual average rate of growth(AARG)and sorting ratio(RM). Results There were 6 major varieties of traditional AEDs,including dilantin, carbamazepine, sodium valproate and phenobarbital. The sodium valproate had two subcategories, the common homemade tablets and controlled-release tablets jointly made by home and abroad companies. The carbamazepine also had two subcategories,the common homemade tablets and tablets jointly made by home and abroad companies. New AEDs had 5 varieties including levetiracetam,lamotrigine,oxcarbazepine,topiramate and gabapentin. Between 2010 and 2013,the sales amount and DDDs of AEDs increased year by year with an AARG of 13. 85%;controlled - release tablets of sodium valproate, sodium valproate and oxcarbazepine remained the top three in the four years. New AEDs(16. 93 -36. 28)were distinctly higher than traditional AEDs(0. 38-5. 22)in DDC,and both of them had RM higher than 1. Conclusion Economic factors affect the choice of AEDs. The traditional AEDs are still the primary choice for treatment. The independent research and development of new AEDs should be strengthened and promoted in order to reduce the drug price and bring benefit to patients.关键词
抗惊厥药/用药频度/日均费用/年均增长率/应用分析Key words
Anticonvulsants/Defined daily doses/Defined daily cost/Average annual rate of growth/Analysis of drug use分类
医药卫生
