艾克拜尔·亚里坤 1乌拉别克·毛力提 1刘宇利 2杨小朋1
作者信息
- 1. 830001 新疆维吾尔自治区人民医院神经外科
- 2. 新疆医科大学研究生学院
- 折叠
摘要
Abstract
Objectjve To investigate the efficacy of three operation methods in the treatment of Arnold - Chiari Ⅰmalformation with syringomyelia and provide references for clinical treatment. Methods Retrospective analysis was conducted on 113 patients with Arnold - Chiari Ⅰ malformation and syringomyelia who were admitted into the Department of Neurosurgery of People′s Hospital of Xinjiang Uygur Autonomous Region from January 2006 to June 2012. The included patients were divided into three groups:group A( n = 16 ),group B( n = 55 ) and group C( n = 42 ). Group A was treated with pure bony decompression;group B was treated with bony decompression plus dural enlargement repair;group C was treated with bony decompression plus dural enlargement repair and resection of cerebellar tonsils. Operation effective rate,incidence of the operation complications shortly after surgery and spinal cord cavity closure rate were compared among the three groups. Results A,B,C group were 12,45,46 patients followed up for 6 months - 2 years. The operation effective rates of group A,B and C were 41. 7% (5 cases),91. 1%(41 cases)and 88. 9% (32 cases),with group B and group C significantly higher(P <0. 05)than group A. The spinal cord cavity closure rates of group A,B and C were 33. 3% (4 cases),80. 0% (36 cases) and 75. 0% (27 cases),with group B and group C significantly higher(P < 0. 05)than group A. The incision infection rates of group A,B and C were 12. 5% (2 cases),14. 5% (8 cases)and 14. 2% (6 cases)and the transient headache rates were 37. 5% (6 cases),54. 5% (30 cases),59. 5% (25 cases),with no significant differences( χ2 = 0. 044,0. 276;P >0. 05). The rates of early leakage of cerebrospinal fluid with subcutaneous hydrops of group A and B were 27. 3% (15 cases) and 31. 0% (13 cases)and it was not noted in group A. One patient of group C died. Conclusjon Bony decompression plus dural enlargement repair and bony decompression plus dural enlargement repair and resection of the cerebellar tonsils have similar effects with high effective rates,low complication rates and better overall effects than pure bony decompression. The two operation methods are recommendable for the treatment of Arnold - Chiari Ⅰ malformation with syringomyelia.关键词
Arnold - Chiari 畸形/脊髓空洞症/神经外科手术/疗效比较研究Key words
Arnold - Chiari malformation/Syringomyelia/Neurosurgical procedures/Comparative effectiveness research分类
医药卫生
