中国全科医学Issue(17)：2005-2008,2009,5.DOI:10.3969/j.issn.1007-9572.2015.17.005
代谢综合征与臂踝脉搏波速度的关系
Relationship Between Metabolic Syndrome and Brachial -ankle Pulse Wave Velocity
摘要
Abstract
Objective To investigate the relationship between metabolic syndrome( MS) and brachial-ankle pulse wave velocity( baPWV). Methods A total of 692 patients who were admitted into the Cardiovascular Research Center of Union Hospital of Huazhong University of Science and Technology from October 2010 to October 2013 were enrolled. We determined a series of basic MS syndromes,including overweight or obesity,excessive waistline( male≥90 cm;female≥80 cm),abnormal glucose tolerance or diabetes mellitus,hypertension. According to different components,272 subjects with only basic MS syndromes were assigned into the MS1 group,270 subjects with both basic MS syndromes and abnormal TG were assigned into the MS2 group,and 150 subjects with both basic MS syndromes and abnormal HDL-C were assigned into MS3 group. Another 300 health subjects were enrolled as the control group. The venous blood of the subjects was sampled,and then tests were conducted on TC,TG,LDL-C,HDL-C,FPG,2 hPG and hs-CRP. The baPWV of the subjects was also measured. Results The four groups were significantly different(P<0. 05)in age,body weight,BMI,waistline,SBP,DBP,PP,MAP,TC,TG, LDL-C,HDL-C,FPG,2 hPG, hs-CRP and baPWV;MS1 group, MS2 group, MS3 group were higher ( P <0. 05 ) than the control group in age,body weight,BMI,waistline,SBP,DBP,PP,MAP,FPG,2 hPG,hs-CRP and baPWV;MS2 group and MS3 group were higher(P<0. 05)than MS1 group in body weight,BMI,waistline,SBP,DBP,PP,MAP, FPG,2 hPG and baPWV;MS3 group was higher ( P <0. 05 ) than MS2 group in the waistline of males, SBP, PP, TC, LDL-C and baPWV. The rectilinear correlation analyses showed that age,BMI,SBP,PP,MAP,TG,FPG,2 hPG were positively correlated with baPWV,and DBP and HDL-C were negatively correlated(P<0. 05)with baPWV. The multivariate linear regression correlation analyses showed gender,age,BMI,SBP,DBP,2 hPG and TG were influencing factors for baPWV of MS patients( P<0. 05 ). Conclusion More abnormal MS components are associated with severer arteriosclerosis. Gender,age,BMI,blood pressure,2 hPG,TG are influencing factors for the increase in baPWV of MS patients. The monitoring on baPWV of MS patients is helpful for the forecast evaluation of cardiovascular events.关键词
代谢综合征X/臂踝脉搏波速度/血管硬化Key words
Metabolic syndrome X/Brachial-ankle pulse wave velocity/Vascular stiffness分类
医药卫生引用本文复制引用
唐世凡,王朝晖,董晓雁,张艳霞,王艳芳..代谢综合征与臂踝脉搏波速度的关系[J].中国全科医学,2015,(17):2005-2008,2009,5.基金项目
2010年湖北省武汉市卫计委临床医学科研基金项目 （）
