摘要
Abstract
Objective To investigate the clinical and imaging features and risk factors of aortic arch cerebral infarction in order to provide references for clinical diagnosis and treatment. Methods We enrolled 105 patients who were admitted into the Department of Neurology of the First Affiliated Hospital of Wenzhou Medical University from January 2012 to May 2014 with complete clinical data. Among the patients,there were 46 patients with acute cerebral infarction whose MRI suggested cerebral infarction occurred lately,and the rest 59 patients were not diagnosed with cerebral infarction before and during hospital stay. For all subjects,aortic arch atherosclerosis was noted by CTA,while no obvious lesion was found in cervical vertebra artery, intracranial artery and heart. Retrospective analyses were conducted on clinical manifestation,imaging features of brain MRI and risk factors. Results The average NIHSS score was 3. 5. The numbers of subjects who had lesion in left hemisphere,right hemisphere,brainstem,epencephalon,two cerebral hemispheres and both anterior and posterior cerebral circulatory systems were 13,14,11,3,2,and 3 respectively. Long smoking history〔OR(95% CI) =9. 656(2. 177,42. 829),P =0. 003〕,elevated HbA1c〔OR(95%CI) =7. 353(1. 315,41. 103),P=0. 023〕,hypertension〔OR(95%CI) =3. 413 (1. 139,7. 231),P=0. 002〕and elevated LDL -C〔OR(95%CI) =2. 972(1. 026,8. 609),P =0. 045〕were risk factors. Conclusion Aortic arch cerebral infarction is in a mild condition and progresses slowly. Cerebral infarction in internal carotid arterial system is more common than that in vertebrobasilar system. Nidus on each side of hemisphere is not evidently different from each other,both with small size and in the shape of spot and plaque. For patients with cerebral infarction who are in mild condition and have small nidus and unclear cause,if they have long smoking history,elevated HbA1c ,hypertension and elevated LDL -C,aortic arch atherosclerosis should be cautioned.关键词
脑梗死/主动脉,胸/动脉粥样硬化/危险因素Key words
Brain infarction/Aorta,thoracic/Atherosclerosis/Risk factors分类
医药卫生
