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福建省临床分离非结核分枝杆菌菌种分布研究

黄明翔 万康林 陈力舟 张丽水 李丹

中国人兽共患病学报Issue(12):1227-1230,4.
中国人兽共患病学报Issue(12):1227-1230,4.DOI:10.3969/cjz.j.issn.1002-2694.2014.12.012

福建省临床分离非结核分枝杆菌菌种分布研究

Distribution of nontuberculous mycobacteria of clinical mycobacterium isolates f rom Fujian Province,China

黄明翔 1万康林 2陈力舟 1张丽水 1李丹1

作者信息

  • 1. 福建省福州肺科医院/福建医科大学临床教学医院,福州 350008
  • 2. 中国疾病预防控制中心传染病预防控制所/传染病预防控制国家重点实验室,北京 102206
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摘要

Abstract

ABSTRACT:To understand the species distribution of nontuberculous mycobacteria (NTM ) in Fujian Province of China , we collected clinical Mycobacterium isolates in the Fuzhou Pulmonary Hospital from 2009 to 2012 .A total of 6 362 clinical My‐cobacteria isolates were identified as 5 713 (89 .8% ) M .tuberculosis complex and 649 (10 .2% ) NTM strains by conventional identification method .Then ,by means of hsp65‐and rpoB‐PCR‐RFLP methods ,649 NTM strains were identified as 24 spe‐cies or complex of NTM ,in which the top three species or complex with the highest occurrence frequency were M .intracellular , M .avium and M .abscessus ,accounting for 48 .5% ,21 .3% and 12 .5% respectively .The prevalence rate of NTM was 10 .2%among Mycobacterium culture‐positive patients .There are lots of NTM species infecting human being ,and the most prevalence NTM species was M .avium complex accounting for 67 .8% in Fujian Province .

关键词

非结核分枝杆菌/PCR-RFLP/菌种鉴定

Key words

nontuberculous mycobacterium/PCR-RFLP/species identification

分类

医药卫生

引用本文复制引用

黄明翔,万康林,陈力舟,张丽水,李丹..福建省临床分离非结核分枝杆菌菌种分布研究[J].中国人兽共患病学报,2014,(12):1227-1230,4.

基金项目

福建省卫生厅青年科研课题基金项目(No .2010-2-75)资助 ()

中国人兽共患病学报

OA北大核心CSCDCSTPCD

1002-2694

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