中国人兽共患病学报Issue(3)：227-231,5.DOI:10.3969/cjz.j.issn.1002-2694.2015.03.008
2010年福建省肠道病毒71型血清流行病学调查
Sero-epidemiological investigation of Enterovirus 71 antibodies in Fujian Province,China,2010
摘要
Abstract
In order to investigate EV71 antibody levels among general population from Fujian Province after the 2008‐2009 HFMD epidemics ,390 sera‐specimens were collected from 390 participants in 2010 .EV71‐specific antibody was detected by neutralization test ,indicating 186 (47 .69% ) sera of 390 were EV71‐seropositive .Although the difference by gender was not statistically significant on positive rates and antibody titers ,significant differences were observed in positive rates and antibody titers among age groups .The positive rate was increasing with age ,while the 0 age‐group yielded the lowest positive rate of 16 .67% .Subsequently ,significant difference was detected among positive rates and antibody titers between age groups of 0 to 4 years‐old and 5‐years‐old ,with the positive rate of 25 .33% and 61 .67% ,respectively .Therefore ,the EV71 antibody levels among general population from Fujian Province after the 2008‐2009 HFMD epidemics was still in the low level ,especially the age groups of 0 to 4 years‐old .The epidemic of HFMD mainly caused by EV71 will still occur in the future ,and children under 5 years old are major susceptible population ,continuously intensive surveillance ,prevention and control are required .关键词
肠道病毒71型/中和抗体/血清流行病学调查Key words
Enterovirus 71/neutralizing antibody/seroepidemiology survey分类
医药卫生引用本文复制引用
王金章,陈炜,翁育伟,何文祥,张拥军,黄萌,谢剑锋,郑奎城,严延生..2010年福建省肠道病毒71型血清流行病学调查[J].中国人兽共患病学报,2015,(3):227-231,5.基金项目
国家科技重大专项《艾滋病和病毒性肝炎等重大传染病防治》（2012ZX10004-210-003）Supported by the National Mega-Project of Science & Technology for Infectious Diseases in China （No ．2012ZX10004-210-003） Corresponding author Yan Yan-sheng ，Emailyysh＠ fjcdc ．com ．cn （）
