摘要
Abstract
Objective:To investigate the clinical curative effect of intrauterine administration,rectal administration,oral administration of misoprostol for the prevention of cesarean section hemorrhage.Methods:666 cases of pregnant women were selected from January 2013 to January 2014.They were randomly divided into the intrauterine administration group,the rectal administration group and the oral group with 222 cases in each.Three groups were given 20μg uterine oxytocin injection after the delivery of fetus.Three groups were respectively given 400μg misoprostol by the intrauterine administration,rectal administration and oral administration.Results:In the intrauterine administration group,the amount of intraoperative bleeding,the average amount of bleeding of postpartum 2 hours,the average amount of bleeding of 24 hours were 125.8±42.1ml,199.8±39.6ml,229.6±39.2ml. In the rectal administration group,the amount of intraoperative bleeding,the average amount of bleeding of postpartum 2 hours,the average amount of bleeding of 24 hours were 187.8±48.5ml,225.3±61.2ml,305.3±61.2ml.In the oral group,the amount of intraoperative bleeding,the average amount of bleeding of postpartum 2 hours,the average amount of bleeding of 24 hours were 131.2±40.9ml,205.8±42.1ml,258.9±55.1ml.The amount of intraoperative bleeding of the intrauterine administration group and the oral group were significantly better than that of the rectal administration group (P<0.05).The average amount of bleeding of postpartum 2 hours had no significant difference between the three groups(P>0.05).The average amount of bleeding of 24 hours of the intrauterine administration group and the oral group were significantly better than that of rectal administration group(P<0.05).The amount of bleeding of the intrauterine administration group was slightly lower than that of the oral group.1 case was postpartum hemorrhage in the intrauterine administration group,the incidence of bleeding was 0.045%.4 cases were postpartum hemorrhage in the rectal administration group,the incidence of bleeding was 1.8%.1 case was postpartum hemorrhage in the oral group,the incidence of bleeding was 0.045% .There were significant difference between three groups(P<0.05).Conclusion:Intrauterine administration of misoprostol is the best route of administration for the prevention of cesarean section hemorrhage.关键词
剖宫产/米索前列醇/宫内给药/直肠给药/口服给药Key words
Cesarean section/Misoprostol/Intrauterine administration/Rectal administration/Oral administration
