中国社区医师Issue(15)：26-26,28,2.DOI:10.3969/j.issn.1007-614x.2014.15.14
吡格列酮联合胰岛素治疗2型糖尿病的疗效观察
Curative effect observation of pioglitazone combined with insulin in the treatment of type 2 diabetes
冯翠娥1
作者信息
- 1. 112700辽宁省铁法煤业集团总医院内分泌科
- 折叠
摘要
Abstract
Objective:To explore the curative effect of pioglitazone combined with insulin in the treatment of type 2 diabetes. Methods:62 patients with type 2 diabetes who had poor effect treated with diet control and insulin alone were selected,who added pioglitazone treatment.At the forth week and twelfth week after the start of treatment,we measured fasting blood glucose(FPG),2 hours postprandial blood glucose(2hPG) and glycosylated hemoglobin(HbA1c),and observed the changes of insulin dosage, incidence of hypoglycemia and adverse reaction.Results:At the forth week and twelfth week after the start of treatment with pioglitazone combined with insulin,FPG,2hPG and HbAlc were significantly lower than that before treatment(P<0.01).Daily insulin dosage was reduced from 75 ± 7U to 30 ± 3U(P<0.01).The incidence of hypoglycemia was significantly decreased. Individual patients appeared adverse reaction of mild lower limb edema.Conclusion:For the patients with type 2 diabetes who had poor effect treated with diet control and insulin alone,the application of pioglitazone can get a lasting improvement of blood sugar, reduce the insulin dosage of a whole day and improve insulin resistance.And adverse reactions are mild.关键词
吡格列酮/胰岛素 2型糖尿病Key words
Pioglitazone/Insulin/Type 2 Diabetes引用本文复制引用
冯翠娥..吡格列酮联合胰岛素治疗2型糖尿病的疗效观察[J].中国社区医师,2014,(15):26-26,28,2.
