摘要
Abstract
Objective:To investigate the significance of determining serum procalcitonin level in patients with acute exacerbation of chronic obstructive pulmonary disease.Methods:286 cases with AECOPD were selected from January 2013 to January 2014. They were randomly divided into the observation group and the control group with 143 cases in each.The control group were checked blood tests in 1,4,7,10,14 days,and to determine the need for antibiotic treatment according to the clinical symptoms, signs and laboratory test.The observation group were added serum PCT examination based on the control group treatment,and determined whether the use of antibiotics according to the PCT examination results.Results:In 143 cases of the observation group, 103 cases were PCT positive,and the positive rate was 72%.85 cases were hs-CRP positive,and the positive rate was 59.4%.There were significant difference(P<0.05).In the observation group,the average duration of antibiotics use was 8.1±1.9 days,and the hospitalization time was 11.2±19 days,7 cases of double infection,accounting for 4.9%.In the control group,the average duration of antibiotics use was 22.3±5.7 days,and the hospitalization time was 22.2±7.8 days,34 cases of double infection,accounting for 23.8% .There were significant difference between two groups(P<0.05).Conclusion:The level of serum procalcitonin is an important index to assess whether the use of antibiotics,and it has important clinical significance for the rational use of antibiotics.关键词
慢性阻塞性肺疾病/降钙素原/抗生素Key words
Chronic obstructive pulmonary disease/Serum procalcitonin/Antibiotics
