中国社区医师Issue(18)：24-24,26,2.DOI:10.3969/j.issn.1007-614x.2014.18.12
氯沙坦与培哚普利联用对老年高血压左室肥厚及血浆纤维蛋白原的影响
Influence of losartan combined with perindopril on older hypertensive left ventricular hypertrophy and plasma fibrinogen
李淑兰 1丁召兴 2薄其美 3耿花娥4
作者信息
- 1. 256600山东省滨州市滨州医学院附属医院住院一部药房
- 2. 256600山东省滨州市滨州医学院附属医院药学部
- 3. 256600山东省滨州市滨州医学院附属医院妇一病房
- 4. 256600山东省滨州市中医院西药房
- 折叠
摘要
Abstract
Objective:To explore the influence of losartan combined with perindopril on older hypertensive left ventricular hypertrophy and plasma fibrinogen.Methods:90 elderly cases with essential hypertension and left ventricular hypertrophy were selected from 2012 to 2013.All cases were treated with losartan and perindopril treatment.Before treatment and at 6 months after the treatment,they received cardiac ultrasound examination to determinate the left ventricular mass index(LVMI).At the same time, they received the plasma fibrinogen(Fg) detection.We observed the changes of left ventricular mass index and the content of fibrinogen of all patients before and after treatment.Results:Compared before and after treatment,LVMI and Fg content were decreased.The difference was statistically significant(P<0.05).Conclusion:The application of losartan combined with perindopril in the treatment of hypertension in the elderly,can reverse left ventricular hypertrophy,and decrease the content of Fg.It is worthy of clinical application.关键词
高血压/左室肥厚/血浆纤维蛋白原/氯沙坦/培哚普利Key words
Hypertension/Left ventricular hypertrophy/Plasma fibrinogen/Losartan/Perindopril引用本文复制引用
李淑兰,丁召兴,薄其美,耿花娥..氯沙坦与培哚普利联用对老年高血压左室肥厚及血浆纤维蛋白原的影响[J].中国社区医师,2014,(18):24-24,26,2.
