中国社区医师Issue(20)：95-95,97,2.DOI:10.3969/j.issn.1007-614x.2014.20.56
视黄醇结合蛋白4与多囊卵巢综合征代谢紊乱的关系
Investigation of the relationship between retinol binding protein 4 and polycystic ovary syndrome metabolic disorder
摘要
Abstract
Objective:To explore the relationship between retinol binding protein 4 and metabolic disorder in patients with polycystic ovary syndrome.Methods:76 PCOS cases were selected.40 healthy volunteers and patients with tubal infertility were selected over the same period.According to BMI and age,they were divided into 28 cases of reproductive period obese PCOS patients(age>19 years old, BMI≥25 kg/m2),22 cases of adolescent obesity PCOS patients(BMI≥25 kg/m2,age≤19 years),14 cases of childbearing age non obese PCOS patients(age>19 years, BMI<25 kg/m2),12 adolescent with non obese PCOS patients(age<19 years,BMI<25 kg/m2),28 cases of childbearing age in control group,12 cases of adolescent control group.We detected blood lipid,glucose tolerance test and insulin release test.The retinol binding protein 4 level was measured by enzyme linked immunosorbent assay retinol binding protein.Results:In the retinol binding protein 4 level,PCOS obese patients of reproductive ages was higher than that in the control group,and there was statistical significance.Correlation analysis showed that retinol binding protein 4 levels were positively associated with triglyceride.Conclusion:Retinol binding protein 4 is associated with PCOS disorder of lipid metabolism,but not correlated with insulin resistance.关键词
多囊卵巢综合征/代谢紊乱/视黄醇结合蛋白4Key words
Polycystic ovary syndrome/Metabolic disorder/Retinol binding protein 4引用本文复制引用
阴红,覃秀..视黄醇结合蛋白4与多囊卵巢综合征代谢紊乱的关系[J].中国社区医师,2014,(20):95-95,97,2.基金项目
科研项目本文为中山市卫生局立项课题(项目编号J2011117《多囊卵巢综合征代谢紊乱的特点及与脂肪因子的相关性研究》)This is the Zhongshan City Health Bureau project(project number:J2011117."Study on the characteristic of metabolic disorder of polycystic ovarian syndrome and correlation with fat factor") （项目编号J2011117《多囊卵巢综合征代谢紊乱的特点及与脂肪因子的相关性研究》）
