中国社区医师Issue(22)：9-9,11,2.DOI:10.3969/j.issn.1007-614x.2014.22.3
生脉饮复方制剂对病毒性心肌炎细胞凋亡作用的研究
Study on the apoptosis effect of pulse-activating decoction compound preparation in viral myocarditis
熊丽辉 1孙大中2
作者信息
- 1. 130117长春中医药大学基础医学院
- 2. 510006广州中医药大学2012级中医学专业实验班 广东广州市
- 折叠
摘要
Abstract
Objective:To study the effect of pulse-activating decoction compound preparation in myocardial apoptosis effect of viral myocarditis.Methods:Using coxsackie B virus established infectious myocardial cell model.In 24 hours after infection,the cells were divided into four groups:the normal control group,the pathological model group,the pulse-activating decoction group and the coenzyme Q10 group.The cellular morphology of four groups of cells were observed at different time points.The apoptosis was detected by TUNEL method.Results:Begin testing at 48 hours,the normal control group had no apoptosis;the pulse-activating decoction group and the coenzyme Q10 group all had apoptosis;the apoptosis rate of the pulse-activating decoction group was lower than that of the coenzyme Q10 group(P<0.05).In the pathological model group,the apoptosis rate was increased as time goes on.72 hours point was obviously higher than 48 hours point(P<0.01).There had statistically significant compared with the drug intervention group (P<0.05).Conclusion:Pulse-activating decoction can effectively inhibit the myocardial cell apoptosis of viral myocarditis,and it should be early intervented.关键词
生脉饮/病毒性心肌炎/细胞凋亡Key words
Pulse-activating decoction/Viral myocarditis/Apoptosis引用本文复制引用
熊丽辉,孙大中..生脉饮复方制剂对病毒性心肌炎细胞凋亡作用的研究[J].中国社区医师,2014,(22):9-9,11,2.
