中国社区医师Issue(22)：75-76,2.DOI:10.3969/j.issn.1007-614x.2014.22.45
帕罗西汀联合小剂量奥氮平治疗老年抑郁症的临床观察
Clinical observation of paroxetine combined with small dose of olanzapine in the treatment of senile depression
乔泽国 1郭彩娥 1张玉英 1刘彩云 1吴恩海 1周海霞 1高云香1
作者信息
- 1. 056001河北邯郸市第一医院东区 原邯郸市中西医结合医院 精神科
- 折叠
摘要
Abstract
Objective:To investigate the clinical efficacy and safety of paroxetine combined with olanzapine in the treatment of senile depression.Methods:66 cases with depression were randomly divided into the study group and the control group.The study group were treated with paroxetine combined with olanzapine.The control group were only treated with paroxetine.They were observed for 8 weeks.We assessed the efficacy by the Hamilton Depression Scale(HAMD),Hamilton Anxiety Scale(HAMA) before and after the treatment of 1 week,2 weeks,4 weeks,8 weeks.We assessed the safety by the Treatment Emergent Symptom Scale(TESS).Results:The curative effect of paroxetine with small dose of olanzapine is significantly.The significant efficiency rate of the study group and the control group were 75% and 51.5% respectively.There was significant difference(P<0.05).Conclusion:Paroxetine Combined with olanzapine in the treatment of depression and anxiety has a rapid onset.It can improve curative effect.关键词
奥氮平/帕罗西汀/抑郁症Key words
Olanzapine/Pa Rossi Dean/Depression引用本文复制引用
乔泽国,郭彩娥,张玉英,刘彩云,吴恩海,周海霞,高云香..帕罗西汀联合小剂量奥氮平治疗老年抑郁症的临床观察[J].中国社区医师,2014,(22):75-76,2.
