中国社区医师Issue(22)：107-107,109,2.DOI:10.3969/j.issn.1007-614x.2014.22.64
抗环瓜氨酸肽抗体在早期类风湿性关节炎诊断中的临床意义
Clinical significance of anti-cyclic citrullinated peptide antibody in the diagnosis of early rheumatoid arthritis
李玉梅 1高翔 1邱迟娥 1宗琳1
作者信息
- 1. 657000云南昭通市第一人民医院血液风湿免疫科
- 折叠
摘要
Abstract
Objective:To detect the sensitivity and specificity of anti-cyclic citrullinated peptide antibody(anti CCP antibody) in the diagnosis of early rheumatoid arthritis,and to study and evaluate the clinical significance of anti CCP antibody detection in the diagnosis of early RA.Methods:In 338 cases of serum specimens,anti CCP antibody and RFIg-A、 RFIg-G、 RFIg-M were detected by enzyme linked immunosorbent assay(ELISA).Results:The specificity of anti CCP antibody was as high as 94.8%;the sensitivity was 94.5%.The sensitivity of RF was 97.2%;the specificity was 71.6%.Conclusion:Anti CCP antibody has a very high diagnostic specificity for RA.Detection combined with RF can improve the accuracy of RA early diagnosis.关键词
抗环瓜氨酸肽抗体/类风湿性关节炎/类风湿因子Key words
Anti-cyclic citrullinated peptide antibody/Rheumatoid arthritis/Rheumatoid factor引用本文复制引用
李玉梅,高翔,邱迟娥,宗琳..抗环瓜氨酸肽抗体在早期类风湿性关节炎诊断中的临床意义[J].中国社区医师,2014,(22):107-107,109,2.
