中国社区医师Issue(23):42-43,2.DOI:10.3969/j.issn.1007-614x.2014.23.26
替比夫定与阿德福韦酯治疗HBeAg阳性慢性乙型肝炎的疗效对比观察
Comparative observation on the curative effect of telbivudine and adefovir dipivoxil in the treatment of HBeAg positive chronic hepatitis B
申纪轩1
作者信息
- 1. 471031解放军第150中心医院门诊部
- 折叠
摘要
Abstract
To explore the clinical effect of telbivudine and adefovir dipivoxil in the treatment of HBeAg positive chronic hepatitis B.Methods:90 cases of HBeAg positive chronic hepatitis B were selected from 2012 to 2013.They were divided into the observation group and the control group with 45 cases in each.The observation group were treated with telbivudine.The control group were treated with adefovir dipivoxil.They were given continuous treatment for 24 weeks.Results:The liver function of the observation group was better than that of the control group,and the difference was statistically significant(P<0.05).The negative conversion ratios of HBeAg and HBV-DNA of patients in the observation group were high,and there was significant difference compared with the control group(P<0.05).Conclusion:Telbivudine in the treatment of HBeAg positive chronic hepatitis B has significant effect,and its effect is superior to adefovir dipivoxil.关键词
替比夫定/阿德福韦酯/慢性乙型肝炎/HBeAg阳性Key words
Telbivudine/Adefovir dipivoxil/Chronic hepatitis B/HBeAg positive引用本文复制引用
申纪轩..替比夫定与阿德福韦酯治疗HBeAg阳性慢性乙型肝炎的疗效对比观察[J].中国社区医师,2014,(23):42-43,2.