摘要
Abstract
Objective:To explore the safety and efficacy of etomidate fat emulsion(dose ratio 7:1) or propofol combined with fentanyl in painless gastroscopy.Methods:120 cases with painless gastroscopy were selected from March to August 2013.They were randomly divided into the etomidate fat emulsion group(group A) and the propofol group(B group).They were anesthetized respectively combined with fentanyl.We observed the HR,SPO2,MAP,drug onset time,operation time,recovery time of patients,the number of cases with myoclonus,the number of cases of nausea and vomiting of the two groups.We compared the efficacy of the two groups.Results:There was no significant difference in drug onset time,operation time and recovery time of the two groups. During the operation,etomidate fat emulsion group(A group) had myoclonus in 18 cases;the propofol group(B group) was 1 case. After the operation,etomidate fat emulsion group(A group) had 7 cases of nausea,vomiting;the propofol group(B group) was 2 cases. In group B,MAP,HR were lower than that before operation(P<0.05).Conclusion:Etomidate fat emulsion or propofol combined with fentanyl can be used for gastroscopy,and achieve satisfactory results.The cardiovascular inhibition of propofol is stronger than etomidate myoclonus,and the postoperative incidence of nausea and vomiting is lower than etomidate.关键词
依托咪酯脂肪乳/丙泊酚/无痛胃镜Key words
Etomidate fat emulsion/Propofol/Painless gastroscopy