中国社区医师Issue(30)：28-30,3.DOI:10.3969/j.issn.1007-614x.2014.30.15
血栓抽吸联合替罗非班治疗急性ST段抬高性心肌梗死的疗效分析
Clinical effects analyzing of thrombus aspiration combined with tirofiban in the treatment of acute ST-segment elevation myocardial infarction
桂亮 1吴斌 1张亮 1李卫萍 1袁震杨 1青岳1
作者信息
摘要
Abstract
Objective:To explore the clinical effects of thrombus aspiration combined with tirofiban in the treatment of acute ST-segment elevation myocardial infarction(ASTEMI).Methods:46 cases of ASTEMI as the control group from January to December in 2011 were treated with simple PCI combined with tirofiban.60 cases of ASTEMI as the treatment group from January to December in 2011 were treated with thrombus aspiration,intravascular tirofiban for injection and PCI combined with intravascular tirofiban postoperative.The indicators including postoperative TIMI flow grade,ST-segment resolution 1.5 h after surgery,the time to peak of creatine kinase isoenzyme,left ventricle ejection fraction 30 d after surgery,major cardiovascular events and bleeding events post-discharge of the two groups were observed.Results:The ST-segment resolution rate of the treatment group(90%) was significantly higher than that of the control group(73.9%)(P<0.05).The average creatine kinase isoenzyme of the treatment group was lower than that of the control group(P<0.05).The time to peak of creatine kinase isoenzyme of the treatment group was shorter than that of the control group(P<0.05).The left ventricle ejection fraction 30 d after surgery of the treatment group improved more obviously than that of the control group.The incidence of malignant arrhythmia and cardiac insufficiency of the treatment group was lower than that of the control group(P<0.05).Conclusion:Transcatheter thrombus aspiration combined with tirofiban in the treatment of acute ST-segment elevation myocardial infarction can increase the myocardial perfusion effectively and improve the short-term prognosis,which is safeand effective.关键词
急性ST段抬高性心肌梗死/血栓抽吸/替罗非班Key words
Acute ST-segment elevation myocardial infarction/Thrombus aspiration/Tirofiban引用本文复制引用
桂亮,吴斌,张亮,李卫萍,袁震杨,青岳..血栓抽吸联合替罗非班治疗急性ST段抬高性心肌梗死的疗效分析[J].中国社区医师,2014,(30):28-30,3.
