中国社区医师Issue(1)：64-65,2.DOI:10.3969/j.issn.1007-614x.2015.1.38
转移性结肠癌中低剂量阿司匹林与Capox方案联合时增效作用
Synergistic effect of metastatic colorectal cancer treated with Capox regimen combined with moderate and low dose aspirin
曾芳玲1
作者信息
- 1. 410000湖湘中医肿瘤医院 湖南省长沙市
- 折叠
摘要
Abstract
Objective:To explore the different dosing regimens for metastatic colorectal cancer(mCRC) effect.Methods:87 mCRC patients were selected.On the basis of regimen,they were divided into the observation group with 44 cases and the control group with 43 cases.The control group were given Capox regimen treatment,and the observation group were given the Capox regimen combined with low dose aspirin treatment.We compared the treatment effect.Results:OR of the two groups respectively was 48.8%and 54.5%,and there was no significant difference(P>0.05).DCR of the two groups respectively was 67.4% and 88.6%,and the difference was statistically significant(P<0.05).In the two group,1 year survival rate respectively was 55.8% and 79.5%;3 years survival rate respectively was 34.9% and 61.4% ;the difference was statistically significant(P<0.05).There was no significant difference between the two groups of adverse reaction.Conclusion:Capox regimen combined with low dose aspirin therapy in patients with mCRC can significantly increase the efficacy and not increase adverse reactions.关键词
转移性结肠癌/中低剂量阿司匹林/Capox方案Key words
Metastatic colorectal cancer/Moderate and low dose aspirin/The Capox scheme引用本文复制引用
曾芳玲..转移性结肠癌中低剂量阿司匹林与Capox方案联合时增效作用[J].中国社区医师,2015,(1):64-65,2.
