中国社区医师Issue(2)：107-108,2.DOI:10.3969/j.issn.1007-614x.2015.2.68
新疆石河子地区HPV感染的基因型分布特点
The genotype distribution characteristics of HPV infection in Shihezi region of Xinjiang
苟永慧 1廖新华 1程江1
作者信息
- 1. 832000新疆石河子大学医学院第一附属医院检验科
- 折叠
摘要
Abstract
Objective:To investigate the epidemic status and infection subtype distribution of HPV in cervical tissue in Shihezi area of Xinjiang,in order to provide the basis for development of HPV vaccine in this area.Methods:2 250 women were tested DNA genotyping of cervical exfoliated cells of HPV using liquid chip technology,and then statistically analyzed the infection rate of HPV and subtype distribution.Results:Among 2 250 women who were detected in the HPV,537 cases of DNA positive,the total positive rate was 23.87%.25 subtypes(HPV 73 type not found) were detected,in which high-risk subtype infection was 74.12%(398/537),low-risk subtype infection was 17.88% (96/537),mixed infection with high risk subtypes and low-risk subtype was 8.01% (43/537).The most common high-risk subtypes were HPV-16,39,and 55 type;the infection rates were 2.84% (64/2250), 2.49% (56/2250) and 2.13% (48/2250) respectively;the highest infection rate of subtype with low risk HPV were HPV-6 and HPV-11 respectively,while the infection rates were 2.27% (51/2250) and 1.69% (38/2250) respectively.Of with cervical HPV infection rate(33.64% ) and multiple HPV subtype infection rate(30.45% ) women of 25~35 years old were the highest,and differences of HPV infection rate in each age group were statistically significant(P<0.01).Conclusion:HPV subtypes in Shihezi area of Xinjiang is obviously different from other regions,which provides certain reference value to work for HPV vaccination and cervical cancer prevention and treatment in Shihezi area of Xinjiang.关键词
HPV/亚型/宫颈癌Key words
HPV/Subtype/Cervical cancer引用本文复制引用
苟永慧,廖新华,程江..新疆石河子地区HPV感染的基因型分布特点[J].中国社区医师,2015,(2):107-108,2.
