中国社区医师Issue(4)：106-108,110,4.DOI:10.3969/j.issn.1007-614x.2015.4.65
泉州地区儿童社区获得性肺炎的病原学特点及耐药情况分析
Drug resistance situation and etiology characteristics analysis of children with community-acquired pneumonia in Quanzhou area
李联侨 1陈琼华 1颜艺琳 1彭维林 1林志斌1
作者信息
摘要
Abstract
Objective:To explore the etiology characteristics and bacterial drug resistance of children community acquired pneumonia in Quanzhou area,to provide the basis for clinical treatment.Methods:1 746 children with acquired pneumonia were selected from January 2011 to January 2013.The clinical data including etiology constitutes,bacterial drug resistance,clinical manifestation,fiberoptic bronchoscopy,imaging characteristics and auxiliary examination were statistically analyzed.Results:①655 cases(37.5%) were etiology examination positive in 1746 children,mainly infants and young children.②253 cases(38.6%) were bacterial infection;169 cases(25.8% ) were viral infection;97 cases(14.8% ) were pneumonia mycoplasma/chlamydia/legionella pneumophila infection;65 cases(9.9% ) were mixed infection.The bacterial infection was the most common streptococcus pneumoniae,staphylococcus aureus,haemophilus influenzae,moraxella catarrhalis.The virus infection was the most common RSV, influenza,parainfluenza.The atypia bacteria was the most common mycoplasma pneumoniae, chlamydia trachomatis.More than 3 years old children with MP and less than 3 years old children with MP were compared with significant difference(χ2=58.03,P<0.01).Less than 6 months children with two kinds of pathogens mixed infection and more than 1 years old children were compared with significant difference(χ 2=87.1,P<0.01).③In the detection of 87 strains of streptococcus pneumoniae,45 strains were penicillin resistant streptococcus pneumoniae(PRSP);they were all resistance for erythromycin and clindamycin;they were all sensitive to vancomycin.In the detection of 22 strains of extended spectrum-lactamases (ESBLs).Including 13 strains of escherichia coli,9 strains of klebsiella pneumoniae,they were all resistance for ampicillin and cephalosporins antibiotics;they were all sensitive to vancomycin,including 1 strain was resistance for meropenem;they were all sensitive to imipenem.④The detection of procalcitonin and CRP is helpful in differentiating CAP caused by bacteria or virus infection.Conclusion:Children community acquired pneumonia in Quanzhou area is mainly found in infants and young children.Bacteria is mainly streptococcus pneumoniae and staphylococcus aureus,and the virus infection is mainly RSV,influenza,parainfluenza.RSV and mixed infection are more common in less than 6 months infants.The detection of procalcitonin and CRP is helpful in differentiating CAP caused by bacteria or virus infection.To understand local area CAP pathogen characteristics and the detection of procalcitonin and CRP help to avoid the abuse of antibiotics.关键词
社区获得性肺炎/病原体/流行病学特征/儿童Key words
Community acquired pneumonia/Pathogen/Epidemiologic feature/Children引用本文复制引用
李联侨,陈琼华,颜艺琳,彭维林,林志斌..泉州地区儿童社区获得性肺炎的病原学特点及耐药情况分析[J].中国社区医师,2015,(4):106-108,110,4.
