中国社区医师Issue(11)：5-5,7,2.DOI:10.3969/j.issn.1007-614x.2015.11.1
趋化因子CXCL12/SDF-1及其受体CXCR4与系统性红斑狼疮的研究进展
Research progress of chemotactic factor CXCL12/SDF-1 and its receptor CXCR4 and systemic lupus erythemato-sus(sle)
摘要
Abstract
Chemokine as a kind of small cellular factors which can make many kinds of subgroup white blood cells including T and B cells to have chemotactic movement involved in the pathogenesis of various autoimmune diseases.CXCL12 was a member of the CXC chemokines factors family and had biological functions after combination with its receptor CXCR4 including mediated immune inflammatory response,regulating the migration of hematopoietic stem cell homing and angiogenesis,metastasis of malignant tumor,etc.This paper mainly summarized the research progress of CXCL12 and CXCR4 in autoimmune disease such as systemic lupus erythematosus(sle).关键词
系统性红斑狼疮/趋化因子/CXCL12/CXCR4Key words
Systemic lupus erythematosus (sle)/Chemokines/CXCL12/CXCR4引用本文复制引用
吴晓蓓,苏美华,马天骄,毕黎琦..趋化因子CXCL12/SDF-1及其受体CXCR4与系统性红斑狼疮的研究进展[J].中国社区医师,2015,(11):5-5,7,2.
