摘要
Abstract
Objective:To analyze the hypersensitive c-reactive protein(hs-CRP) changes of rosuvastatin calcium in the treatment of diffuse coronary artery lesion.Methods:160 patients with coronary arteriography were selected from February 2013 to May 2014. The hs-CRP was detected before operation.In 80 cases of the observation group,the arteriography result showed that three vessel stenosis were more than 50%,the lesion lengths were greater than or equal to 20 mm,the patients were treated by rosuvastatin calcium 10 mg/d for 6 months.In 80 cases of the control group,the coronary arteriography results were completely normal.The hsCRP expression levels of two groups and hs-CRP expression change after treatment of the observation group were compared. Results:Before treatment,the hs-CRP of the observation group was (7.39±2.46)mg/L,the control group was (4.39±0.89)mg/L,the difference was statistically significant(P<0.05).After 6 months of treatment,the serum hsCRP level of the observation group reduced to (4.26 ± 0.33)mg/L,the difference between hs-CRP expression level after treatment and before treatment was statistically significant(P<0.05).Conclusion:Hs-CRP plays an important role in the occurrence and development of diffuse coronary artery lesion.Rosuvastatin calcium can significantly decrease the serum hs-CRP level,reduce the adverse cardiovascular events, and improve the prognosis of patients.关键词
瑞舒伐他汀钙/冠心病/hs-CRPKey words
Rosuvastatin calcium/Coronary heart disease/Hs-CRP
