中国实验动物学报Issue(2)：194-198,5.DOI:10.3969/j.issn.1005-4847.2015.02.017
四个不同种属动物肢体 II导联心电图比较
Comparison of the ECG lead II characteristics in four different species of animals
谭莹 1那敏 1王京昆 1苏敏 1廖伟 1史新辉 1杨宏博 1毛勇 1徐红花 1师廷川 1李勇1
作者信息
- 1. 云南白药集团创新研发中心，云南省药物研究所，云南省中药和民族药新药创制企业重点实验室，昆明 650111
- 折叠
摘要
Abstract
Objective The ECG lead II characteristics of Beagle dog, rhesus monkey, Japanese white rabbit and tree shrew were analyzed and summarized to provide reference for drug safety evaluation studies.Methods The ECG lead II of healthy adult Beagle dog, rhesus monkey, Japanese white rabbit and tree shrew were recorded to determine the interval of P, PR, QT ( QTc) , the QRS waves and amplitude of P, R, T waves and the ST shift.Results and Conclusion All the animals had sinus rhythm.All the four species of animals had similar ECG pattern with no particular specific changes, but had some differences of the QRS wave group and T wave.The amplitude of P and T waves in Japanese white rabbit was smaller, and the heart rate of tree shrew was faster than that of the other species of animals.The ECG leadⅡdatabase of the Beagle dog, rhesus monkey, Japanese white rabbit and tree shrew is established.关键词
比格犬/恒河猴/日本大耳白兔/树鼩/心电图,ECG-IIKey words
Beagle dog/Rhesus monkey/Japanese white rabbit/Tree shrew/ECG laed II分类
生物科学引用本文复制引用
谭莹,那敏,王京昆,苏敏,廖伟,史新辉,杨宏博,毛勇,徐红花,师廷川,李勇..四个不同种属动物肢体 II导联心电图比较[J].中国实验动物学报,2015,(2):194-198,5.
