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实验树鼩主要内分泌器官的组织学观察

匡德宣 孙晓梅 陆彩霞 王文广 仝品芬 殷安国 李晓飞 代解杰

中国比较医学杂志Issue(6):35-39,5.
中国比较医学杂志Issue(6):35-39,5.DOI:10.3969/j.issn.1671.7856.2014.006.008

实验树鼩主要内分泌器官的组织学观察

Histological observation of the major endocrine organs in laboratory tree shrews

匡德宣 1孙晓梅 1陆彩霞 1王文广 1仝品芬 1殷安国 1李晓飞 1代解杰1

作者信息

  • 1. 中国医学科学院/北京协和医学院医学生物学研究所树鼩种质资源中心,云南省重大传染病疫苗研发重点实验室,昆明 650118
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摘要

Abstract

Objective To understand the histological characteristics of the major endocrine organs of tree shrew , and provide a normal histological atlas of endocrine organs of tree shrew .Methods Ten artificially fed healthy tree shrews were killed and dissected after anesthesia .The thyroid, parathyroid, adrenal and pituitary glands were observed by gross inspection and samples were taken for routine histological examination with HE staining .Results ( 1 ) The thyroid gland was pale yellow, located on both sides of the 2-4 tracheal rings.The thyroid gland was plate-shaped, its surface was covered with a thin fibrous capsule . The thyroid parenchyma was divided into several lobules by stretched capsule membrane .Follicular and parafollicular cells were distributed in the lobules , and red colloid was present in follicular cavity.(2) Each side had one parathyroid , located on the cranial or the outer surface of the middle part of the thyroid gland, and was slightly covered by thyroid .The gland was round or oval , and its parenchyma was made up of the principal cells and eosinophil cells , and acinar structure appeared in the parenchyma .( 3 ) The adrenal glands were oval , yellow color, located in the renal hili , and linked to the kidneys .They were surrounded by a thin capsule .The parenchyma was divided into cortex and medulla .The cortex was divided into zona glomerulosa , zona fasciculata and zona reticularis from outside to inside.The zona glomerulosa was the thickest layer and the zona fasciculata was the thinnest .The medulla cells formed clumps or mesh, with central vein in the central part .(4) The pituitary gland was located in the sella turcica , with no recessus hypophysis .The pituitary gland was composed of the adenohypophysis and neurohypophysis .Its surface was covered with a connective tissue capsule .The pituitary gland was divided into distal part , middle part and pars tuberalis . neurohypophysis was made up of neural and pars infundibularis .Conclusions The histological atlas of endocrine organs in the tree shrew is established , which is close to that of the primate animals in the morphology , and provide histological evidence for the study of tree shrew endocrine organs and disorders , as well as the animal model of human diseases .

关键词

树鼩/内分泌器官/组织学

Key words

Tree shrews/Endocrine organs/Pituitary gland/Thyroid gland/Parathyroid gland/Adrenal gland/Histology

分类

医药卫生

引用本文复制引用

匡德宣,孙晓梅,陆彩霞,王文广,仝品芬,殷安国,李晓飞,代解杰..实验树鼩主要内分泌器官的组织学观察[J].中国比较医学杂志,2014,(6):35-39,5.

基金项目

“十一五”国家科技支撑计划项目(编号2011BAI15B01-21;2012BAI39B01;2014BAI01B01);云南省科技创新计划平台项目(编号2013DA002);云南省应用基础面上项目(编号2011FZ211;2013FZ132)。 ()

中国比较医学杂志

OA北大核心CSTPCD

1671-7856

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