中国比较医学杂志Issue(8):11-15,23,6.DOI:10.3969.j.issn.1671.7856.2014.008.003
旋毛虫感染黑线仓鼠及其白化突变系后细胞因子变化比较分析
Changes of cytokines in the Cricetulus barabensis and their albino mutant infected with trichinella spiralis
摘要
Abstract
Objective To explore the differences in immune responses between Cricetulus barabensis and their albino mutant infected with Trichinella spiralis.Methods The physiological parameters of blood , expression levels of IL-2 protein and IL-6 gene in the spleen were analyzed.Results The level of immune cells and cytokines of Cricetulus barabensis was higher than that in the albino mutant .Conclusions Cricetulus barabensis is a suitable model animal for research on long-term latent infection such as infection with Trichinella spiralis.关键词
旋毛虫/黑线仓鼠/白化突变系/细胞因子Key words
Trichinella spiralis/Cricetulus barabensis/Albino mutant/Cytokines分类
医药卫生引用本文复制引用
张小飞,刘冉,崔晓霞,马帅,张西臣,白杰英..旋毛虫感染黑线仓鼠及其白化突变系后细胞因子变化比较分析[J].中国比较医学杂志,2014,(8):11-15,23,6.基金项目
军事医学科学院创新基金(2012CXJJ022),动物中心青年基金(QN2011005),“十二五”重大项目(2011zxj09201-031)。 ()