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外环境湿度和换气次数对独立通风笼盒微环境湿度和氨浓度的影响

赵维波 闵凡贵 刘香梅 邝慧文 张钰 刘年双 萨晓婴

中国比较医学杂志Issue(8):36-40,5.
中国比较医学杂志Issue(8):36-40,5.DOI:10.3969.j.issn.1671.7856.2014.008.009

外环境湿度和换气次数对独立通风笼盒微环境湿度和氨浓度的影响

Effect of environmental humidity and ventilation rate on the microenvironmental humidity and ammonia concentration in individually ventilated cages (IVC)

赵维波 1闵凡贵 1刘香梅 1邝慧文 1张钰 1刘年双 2萨晓婴3

作者信息

  • 1. 广东省实验动物重点实验室,广东省实验动物监测所,广州 510663
  • 2. 江苏省实验动物质量检测二站,南京 210008
  • 3. 浙江省医学科学院,杭州 310013
  • 折叠

摘要

Abstract

Objective To assess the changes of humidity and ammonia concentration in rat and mouse individually ventilated cages (IVC) based on macroenvironmental humidity and air ventilation changes .Methods Three kinds of rat and mouse IVC in barrier facilities were set as research objective .The changes of micronvironmental humidity and ammonia concentration at 40 times/h and 60 times /h air changes were detected continuously for a 7-days-cycle relative to low (40%), moderate (50%), and high (60%) macroenvironmental humidity.Results Mouse and rat IVC with 40 times /h air changes under low macroenvironmental humidity condition , mouse IVC with 40 times/h and rat IVC with 60 times/h air changes under moderate macroenvironmental humidity condition , mouse IVC with 60 times /h air changes under high macroenvironmental humidity condition , basically meet the GB14925-2010 requirements.While under macroenvironmental high humidity condition, the microenvironments of rat and mouse IVC with 60 times/h air changes could not satisfy the requirements.Conclusions The environmental humidity and ventilation frequency are the key index of IVC microenvironment.Only on the basis of external environment conditions to set up reasonable IVC ventilation frequency in order to better maintain the IVC microenvironment so that to achieve the goal of effective management .

关键词

IVC/外环境/微环境/换气次数/湿度/氨浓度

Key words

Individually ventilated cage (IVC)/Macroenvironment/Microenvironment/Air Changes/Humidity/Ammonia concentration/Rat/Mouse

分类

医药卫生

引用本文复制引用

赵维波,闵凡贵,刘香梅,邝慧文,张钰,刘年双,萨晓婴..外环境湿度和换气次数对独立通风笼盒微环境湿度和氨浓度的影响[J].中国比较医学杂志,2014,(8):36-40,5.

基金项目

广东省科技计划项目,项目编号[2011B060300034]。 ()

中国比较医学杂志

OA北大核心CSTPCD

1671-7856

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